RxPG - the perfect Rx for medical Post Graduate entrance blues!
Mobile Edition | Help/Newbie? | 24/7 Support
HOT | PrePG | MCQ | DNB | Careers | Books | Colleges | Dental | DocIndia | PLAB |  USMLE  | Australia | Canada | GLOBAL | OffBeat!
Articles | Forums | MCQ Crammer | Downloads | Mnemonics | Revision Tools | Recent Shouts | All Features


Behcet's disease

Author: Wikipedia, Posted on Sunday, September 19 @ 04:35:05 IST by RxPG  

 FRIEND Add to My Pages   PRINTER Printer Friendly   FRIEND Email Story  FRIEND Download Story  Pathology alerts 

Pathology

Behet's disease (BD, or Behet's syndrome) is a rare, multisystem disease with chronic inflammation of blood vessels (i.e. vasculitis). It is also known as Silk Road Disease.

History

Behet's disease is named after Hulusi Behet (1889-1948), the Turkish dermatologist and scientist who first recognized the syndrome in one of his patients in 1924 and reported his research on the disease in Journal of Skin and Veneral Diseases in 1936. The name (Morbus Behet) was formally adopted at the International Congress of Dermatology in Geneva in September 1947.

Benedikt Adamandiades, a Greek ophthalmologist, reportedly described the disease six years before Behet did. Nevertheless, only Greek scientists refer to the disease Adamantiades-Behet's or even Adamantiades' disease.


Pathology

Behet's disease is believed to be caused by an over-active immune system which, without any apparent infections, produces recurrent outbreaks of inflammation in small blood vessels. As a result, symptoms can occur anywhere in the body with a blood supply. Common symptoms include mouth ulcers, sore genitals and eye inflammation, and arthritis in older patients, mostly painful but not life-threatening conditions. However, some patients may be unable to work because of the pain and the impaired vision and mobility. In some severe cases, uncontrolled inflammation may lead to blindness, intestinal complications, stroke, and even meningitis, which can become fatal.

This disease usually first strikes patients in their 20s and 30s. Then, it becomes a lifelong disorder that proceeds in a series of remissions (periods of apparent good health, usually a few months) and exacerbations (periods of active disease and progression, can be a week to a month). Complete remission is rare.


Treatment

There is no cure yet. Current treatment is aimed at easing the symptoms, reducing inflammation, and controlling the immune system.


Epidemiology

Behet's disease is considered more prevalent in the areas surrounding the old silk trading routes in the Middle East and in Central Asia. Thus, it is sometimes known as Silk Road Disease. However, this disease is not restricted to people from these regions.

An estimated 15,000 to 20,000 Americans have been diagnosed with this disease. In the UK, it is estimated to have about 2 cases for every 100,000 people.

Males are affected more frequently than females.



4 (Excellent) 3(Good) 2(Good) 1(Bad)   


Recommended Books for Pathology
 Books to read for Pathology by RxPG

Related Pathology articles
 Chromosomes and Genetic Disorders
 X-Linked Diseases Meltdown
 Autosomal Recessive Disorders Meltdown
 Autosomal Dominant Diseases Meltdown
 Shock Meltdown
 Hypoxia Meltdown
 Origin, Anatomy, Physiology, Developmental Problems & Inflammations in Breast
 Cancer of the Pancreas
 Behcet's disease
 Mesothelioma
 How to understand TNM system?
 Carcinoembryonic Antigen
 Tumor markers
 Tay-Sachs disease
 Hemoglobinopathies
 Tumours of the Central Nervous System
 Multiple Sclerosis and Other Demylinating Disorders
 Neuromuscular and Spinal Cord Pathology
 Cerebrovascular Diseases
 Virtual Pathology Slidebox for Pathology Practical exams

Related Pathology Discussions

Other articles by Wikipedia
 What is a Personal Digital Assistant (PDA) - Overview
 Randomised Controlled Trials (RCT) - Introduction, Classification and Overview
 Overview of Types and Various Phases of Clinical Trials
 What is a Meta Analysis?
 What is a Systematic Review?
 What is a Clinical Audit?
 Oseltamivir (Tamiflu) - First Oral Influenza Neuraminidase Inhibitor
 Clopidogrel - The Super Aspirin
 Donepezil - centrally acting reversible acetyl cholinesterase inhibitor
 Topiramate - A Monosaccharide Anticonvulsant
 Digoxin - Cardiac Glycoside from Foxglove Plant
 Vigabatrin = VIsual side effects + GABA TRansaminase INhibitor
 Olanzapine - Thienobenzodiazepine Atypical Antipsychotic
 Risperidone - Most Commonly Used Atypical Antipsychotic
 Clozapine - The First Atypical Antipsychotic
 Quetiapine - D1 and D2 dopamine antagonist
 Ziprasidone - The Atypical Amongst Atypical Antipsychotics
 Alemtuzumab - Monoclonal Antibody Used in the Treatment of Leukemia and Lymphoma
 Abciximab - A Platelet Aggregation Inhibitor
 Bevacizumab (Avastin) - An Anti-Angiogenesis Anti Cancer Drug

 Pathology FAQ
  Browse all FAQs


Write an Article on Pathology
You can share your exam experiences, preparation strategies, books you have read or just any information about Pathology on RxPG website and we will publish it under your name.

Article Rating
Average Score: 3.5
Votes: 4




Most Read Article
Virtual Pathology Slidebox for Pathology Practical exams

Related Links
· Pathology books at Amazon.com
· RxPG Forums
· Discuss Past Papers
· MRCPath Forum
· MRCpath Section






ARTICLE TOOLS

· Pathology section
· Articles by Wikipedia
· Add to my pages
· Printer friendly version
· PDF version
· Email article
· Feedback on this article
· Medical tutorials
· Related forum posts
· Related articles
· Related downloads
· Submit article
· Pathology alerts
· Pathology books
· Pathology past papers


Most read story about Pathology:
Virtual Pathology Slidebox for Pathology Practical exams



Server Status: 96 pages served in last minute. Page generation time: 0.036 seconds

Site Maps: [Books] [News] [Forums] [Reviews] [Mnemonics]

sitemap - top30 - centuries - testimonials


About Us :: Disclaimer :: Contact Us :: Reporting abuse :: Terms of Services :: Privacy Policy

Advertise with RxPG!
Made in India by RxPG Medical Solutions Private Limited

"RxPG" is a Registered Trademark

Chrome Web Store YouTube Twitter LinkedIn Wikipedia Facebook