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MRCOG Part 1 March 1997 Paper 1

Author: sajida, Posted on Wednesday, April 20 @ 10:00:38 IST by RxPG  

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MRCOG Part 1

MARCH 1997 – PAPER-1

1.Chromaffin cells
a- are innervated by preganglinonic sympathetic fibres
b-are present in adrenal cortex
c-are derived from neuroectoderm
d-can decarboxylate aminoacids
e-are present in celiac ganglion


2-The internal pudendal artery
a-leaves the pelvis through lesser sciatic foramen
b-lies on the medial wall of ischiorectal fossa
c-has a branch which pierces the perineal memberane
d-gives rise to middle rectal artery
e-suppliesthe upper vagina

3-The pelvic splanchnic nerves
a- are derived from posterior ramii of sacral spinal nerves.
b-supply afferent fibres
c-unite with branches of sympathetic pelvic plexus
d- supply the ascending colon with motor fibres
e-supply the uterus with parasympathetic fibres.

4-In the anterior abdominal wall
a-rectus muscle is intersected transversely by three bands
b-posterior rectus sheath below arcuate line consists of transversalis fascia only
c-above the costal margin posterior rectus sheath is deficient
d-superior epigastric artery arises from internal thoracic artery
e-inferior epigastric artery arises from femoral artery

5-The rectum
a- is supplied in part by inferior rectal artery
b-is innervated by inferior rectal nerve
c-is lined by stratified squamous epithelium
d-has its lymphatic drainage to superficial inguinal lymph nodes
e-possess a complete outer layer of longitudinal muscle

6-The obturator nerve
a-emerges from the lateral border of psoas major
b-is formed from the posterior divisions of 2,3,4th lumbar nerves
c-passes lateral to internal iliac vessels
d-lies below the obturator artery in obturator foramen
e-is separated from the normally sited ovary only by pelvic peritoneum

7-In the cerebral cortex
a-the left visual field is represented in the right cerebral cortex
b-the area directly concerned with the movements of hands and face is larger than that concerned with movements of legs and trunk
c-in most people,left side is more concerned with speech than the right side
d-pyramidal cells are present
e-the blood supply is wholly from branches of internal carotid arteries

8-The cervix
a-consists chiefly of smooth muscle
b-has a supravaginal part which is related anteriorly to ureter
c-has a supravaginal part which is covererd with peritoneum anteriorly
d-has pain sensation carried by pelvic splanchnic nerves
e-is lined in its vaginal part by keratinised epithelium

9-The right ureter lies in close relationship to the
a-bifurcation of right common iliac artery
b-infundibulopelvic ligament
c-uterine artery
d-inferior mesenteric artery
e-parietal attachment of sigmoid mesocolon

10-The pelvic surface of the sacrum
a-gives origin to piriformis muscle
b-gives origin to levator ani muscle
c-is broader in male than in female
d-transmits dorsal ramii of sacral nerves
e-is in contact with anal canal

11-In the fetal circulation
a-ductus venosus delivers blood directly into sup. vena cava
b-umbilical artery returns blood from the placenta
c-ducuts arteriosus carries blood to lungs
d-blood returning from lungs is 90% saturated with oxygen
e-blood from the inferior vena cava is largely directed through the foramen ovale

12-The ducuts venosus
a-is part of embryonic heart
b-is a shunt preventing blood from passing to fetal lungs
c-gives rise to ligamentum teres
d-carried blood with a higher PO2 than umbilical arterial blood
e-is derived from anterior cardinal vein

13-The following structures take part in formation of anterior fontanelle in fetal skull
a-lambdoidal suture
b-occipital suture
c-sagittal suture
d-glabella
e-frontal suture

14-Concerning the embryology of urinary tract
a-detrusor has a mesodermal origin
b-urogenital sinus is derived from cloaca
c-allantois gives origin to lateral umbilical ligament
d-metanephric ducts arise from mesonephric ducts
e-mesonephric duct remnants form the epoophoron in the adult female

15-The following tissues are paired with appropriate primary germ cell layer of origin
a-mammary duct epithelium- ectoderm
b-epithelium of tongue –mesoderm
c-pineal gland-ectoderm
d-ovarian stroma-mesoderm
e-endometrium-mesoderm

16-Adrenocorticotrophic hormone
a-production is governed by hypothalamus
b-production is maximal about midnight
c-is present in placenta
d-is increased in maternal plasma in pregnancy
e-secretion is inhibited by glucocorticoids

17-After the menopause
a-the plasma concentration of FSH increases
b-plasma progesterone concentration increases
c-oestrone is the estrogen found in highest concentration in plasma
d-plasma testosterone concentration doubles
e-plasma prolactin concentration increases

18-Successful lactation is
a-maintained by estrogens
b-maintained by progesterones
c-initiated by prolactin surge
d-maintained by human placental lactogen
e-inhibited by dopamine

19-In a woman of reproductive age,serum concentrations of following hormones exhibit a recognised pattern of diurnal variation
a-progesterone
b-melatonin
c-cortisol
d-oestrone
e-FSH

20-Serum concentration of following increase during pregnancy
a-sex hormone binding globulin
b-prolactin
c-total thyroxine
d-FSH
e-17 alpha hydroxy progesterone

21-LH
a-is required for normal corpus luteum survival
b-has a half life in circulation of 30 hrs.
c-is released in pulses
d-in the male stimulates testosterone production
e-plasma concentration is increased in post menopausal women


22-The release of catecholamine from the adrenal medulla increases
a-during sleep in healthy individuals
b-when the nerves to adrenal gland are stimulated
c-following an increase in blood sugar
d-immediately following a myocardial infarction
e-during acute haemorrhage


23-Prolactin
a-release is stimulated by thyrotropin releasing hormone
b-plasma levels are raised in 1st trimester of pregnancy
c-released is increased by suckling
d-may be produced by decidua
e-release is inhibited by metoclopramide

24-HCG
a-is not produced by deciduas
b-is biochemically indistinguishable from LH
c-is active if given to non pregnant women
d-production rises steadily throughout pregnancy
e-has no influence upon the production of estrogens by placenta

25-Huma placental lactogen
a-concentration in maternal plasma is directly proportional to functional mass of placenta
b-has a half life in blood of less than 1 hour
c-is steroid hormone
d-increases the mobilisation of maternal free fatty acids
e-reaches the same concentration in fetal blood as in maternal blood at term


26-The secretion of growth hormone
a-occurs in hypothalamus
b-ceases when the adult state is reached
c-is decreased during stress
d-is increased during fasting
e-is increased with exercise

27-Oxytocin
a-is released episodically
b-causes decreased renal tubular absorption of water
c-is responsible for milk ejection
d-reduces intestinal peristalsis
e-inhibits prolactin secretion

28-Hirsuitism in woman is characterstically associated with
a-testicular feminisation
b-turner syndrome
c-polycystic ovarian syndrome
d-arrhenoblastoma
e-hypopituitarism

29-Parathyroid hormone
a-decreases the renal excretion of phosphate
b-increases calcium resorption from bone
c-depresses pituitary activity
d-concentration in blood are raised when calcium level falls
e-increases renal tubular absorption of calcium

30-Aldosterone
a-reduces sodium reabsorption in the proximal convoluted tubule
b-reduces sodium reabsorptionin descending loop of henle
c-increases sodium reabsorption in distal convoluted tubule
d-increases potassium loss from the tubule
e-increases sodium absorption in the collecting tubule

31-17B estradiol
a-is synthesised by aromatisation of testosterone
b-vasodilates the uterine artery
c-suppresses the uterine activity by upregulating the oxytocin receptor
d-promotes secondary sexual hair growth in females
e-is thrombogenic

32-The germination of tetanus spores in wound is inhibited by
a-tissue trauma
b-oxygen
c-injection of antitoxin
d-injection of toxoid
e-removal of devitalised tissue


33-Proteolytic organisms are secreted by following organisms
a-Neisseria Meningitidis
b-Salmonella typhi
c-Streptococcus pyogenes
d-Mycobacterium tuberculosis
e-Clostridium Perfringens( Welchii)

34-CMV
a-is an adenovirus
b-may be cultured readily in cell free media
c-is a cause of cerebral calcification
d-causes haemolytic anaemia in neonate
e-may be transmitted in saliva

35-Treponema pallidum immobilisation test is positive in
a-yaws
b-infectious mononucleosis
c-malaria
d-chanchroid
e-lyme disease( Borreliosis)


36-Leptospirosis
a-is caused by gram negative coccobacillus
b-is frequently transmitted to man by inanimate objects
c-can result in severe form of jaundice
d-is a STD
e-is transmitted in pasteurised cow’s milk

37-Mycobacteria
a-are non sporing
b-are all acid fast in their staining reaction
c-are facultative anaerobes
d-are responsible for leprosy
e-are all pathogenic in humans

38-Following disorders and organisms are correctly paired
a-Opthalmia neonatrum-Chlamydia trachomatis
b-Chancroid haemophillus ducreyii
c-Sleeping sickness- Leishmaina Donovani
d-Ringworm-Trichinella spirallis
e-non specific urethritis – toxoplasma gondii


39-Following organisms are gram positive
a-Mycoplasma hominis
b-Staphylococcus Aureus
c-Clostridium Perfringens
d-Klebsiella Pneumoniae
e-Bacteroides Fragilis

40-Concerning hepatitis B virus infection
a-Vertical transmission does not occur
b-Sexual transmission occurs
c-Core antigenaemia indicates high infectivity
d-Hepatocellular carcinoma is a recognised complication
e-An effective vaccine is available

41-Following antibiotcs are usually effective against Pseudomona Aeuroginosa
a-Cephradine
b-Amoxycillin
c-carbenicillin
d-gentamicin
e-trimethoprim

42-Recognised unwanted effects of prostaglandin E include
a-water retention
b-increased uterine contractility
c-increased small bowel peristalsis
d-flushing of skin
e-vomiting


43-Following substances are sympathomimetic amines
a-Amphetamine
b-ephedrine
c-histamine
d-isoprenaline
e-chlorpromazine

44-Subcutaneous atropine injection characteristically produces
a-increase in heart rare
b-increase in salivation
c-constriction of pupil
d-hypnotic effect
e-decreased bronchiolar secretion

45-Follwing drugs have anticholinergic effects
a-propatheline bromide
b-carbachol
c-distigmine bromide
d-benzhexol
e-atropine


46-Treatment with morphine
a-causes respiratory depression
b-increases gastric motility
c-causes side effects which may be reversed by naloxone
d-increaes secretion of antidiuretic hormone
e-causes papillary dilatation

47-Hypokalaemia may be caused by
a-bendrofluazide
b-digoxin
c-spironolactone
d-carbenoxolone
e-amiloride

48-Concerning heparins
a-heparin is synthesised in lungs
b-antithrombin III is necessary for standard heparins to exert their anticoagulant effect
c-factor X is inhibited by low molecular weight heparins
d-Low mol wt. heparins have a longer half life than standard heparins
e-penicillins potentiate the action of low mol. wt. heparins
49-The following statistical statements are correct-
a-in the normal distribution,the value of mode is 1.73 times the median
b-in a distribution skew to the right,the mean lies to the left of median
c-in the series- 2;7;5;2;3;2;5;8, the mode is 2
d-student’s ‘t’ test is designed to correct for skew distribution
e-the chi squared testmay be used when data are not normally distributed












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