RxPG - the perfect Rx for medical Post Graduate entrance blues!
Mobile Edition | Help/Newbie? | 24/7 Support
HOT | PrePG | MCQ | DNB | Careers | Books | Colleges | Dental | DocIndia | PLAB |  USMLE  | Australia | Canada | GLOBAL | OffBeat!
Articles | Forums | MCQ Crammer | Downloads | Mnemonics | Revision Tools | Recent Shouts | All Features


Sjogren's Syndrome: Summary and Diagnostic Tests

Author: Guest, Posted on Wednesday, September 10 @ 13:23:13 IST by RxPG  

 FRIEND Add to My Pages   PRINTER Printer Friendly   FRIEND Email Story  FRIEND Download Story  Ophthalmology alerts 

Ophthalmology

Early diagnosis and treatment are important for preventing complications. The symptoms of Sjögren's syndrome may overlap with or “mimic” those of other diseases including lupus, rheumatoid arthritis, fibromyalgia, chronic fatigue syndrome, and multiple sclerosis. Furthermore, dryness can occur for other reasons, such as a side effect of medication like anti-depressants or high blood pressure medication.


Additionally, because all symptoms are not always present at the same time and because Sjögren's can involve several body systems, physicians and dentists sometimes treat each symptom individually and do not recognize that a systemic disease is present. The average time from onset of symptoms to diagnosis is over six years. Rheumatologists have primary responsibility for diagnosing and managing Sjögren's syndrome.

Once Sjögren's syndrome is suspected, a physician will request a series of blood tests, including:

ANA (Anti-Nuclear Antibody)
ANAs are a group of antibodies that react against normal components of a cell nucleus. About 70% of Sjögren's patients have a positive ANA test result.


SSA and SSB
The antibodies SSA (or RO) and SSB (or LA) are often found in Sjögren's syndrome; 70% of patients are positive for SSA and 40% are positive for SSB.


RF (Rheumatoid Factor)
This antibody test is indicative of a rheumatic disease. In Sjögren's patients, 60-70% have a positive RF.


ESR (Erythrocyte Sedimentation Rate)
This test measures inflammation. An elevated ESR can indicate an inflammatory disorder, including Sjögren's syndrome.


IGs (Immunoglobulins)
These are normal blood proteins. They are usually elevated in Sjögren's.
The physician is likely to refer the patient to an ophthalmologist for further tests and to an oral pathologist or dentist for additional procedures.

The ophthalmologic tests include:

Schirmer Test
Measures tear production.


Rose Bengal and Lissamine Green
Uses dyes to observe abnormal cells on the surface of the eye.


Slit-Lamp Exam
Indicates the volume of tears by magnifying the eye and viewing it in its resting state.
The dental tests include:

Parotid Gland Flow
Measures the amount of saliva produced over a certain period of time.


Salivary Scintigraphy
Measures salivary gland function.


Sialography
An x-ray of the salivary-duct system.


Lip Biopsy
Used to confirm lymphocytic infiltration of the minor salivary glands



4 (Excellent) 3(Good) 2(Good) 1(Bad)   


Recommended Books for Ophthalmology
 Books to read for Ophthalmology by RxPG

Related Ophthalmology articles
 Ophthalmology textbook at eMedicine
 Neurological Eye Movement Simulator
 Leucocoria
 Alice in Wonderland syndrome (AIWS)
 Blindness: Vision 2020 - control of major blinding diseases and disorders
 FUNDOSCOPY FINDINGS
 Pupil abnormalities
 AIDS---Ocular involvement
 Sjogren's Syndrome: Summary and Diagnostic Tests
 Dark room procedures for Ophthalmology Practicals: Part 2
 Dark Room Procedures for Ophthalmolgy Practicals: Part 1
 Dark Room Procedures for Ophthalmology Practicals: Part 3
 Stargardt's Disease

Related Ophthalmology Discussions

Other articles by Guest
 Sharing My Experience of PLAB part 2 OSCE
 Buying a Laptop in UK - Some Research
 My experience in PLAB Part 2
 Complications of Acute Myocardial Infarction
 Malignant Hyperthermia
 Hemochromatosis
 Dezocine - A Narcotic Agonist-Antagonist Analgesic
 Porphyrias: Clinical Manifestations, Diagnosis and Treatment
 MRCP Part 1 Paper, 23 Sep 2003 : Version 1.01 - Q 81-155

 Ophthalmology FAQ
  Browse all FAQs


Write an Article on Ophthalmology
You can share your exam experiences, preparation strategies, books you have read or just any information about Ophthalmology on RxPG website and we will publish it under your name.

Article Rating
Average Score: 4
Votes: 2




Most Read Article
Leucocoria

Related Links
· Ophthalmology Books at Amazon






ARTICLE TOOLS

· Ophthalmology section
· Articles by Guest
· Add to my pages
· Printer friendly version
· PDF version
· Email article
· Feedback on this article
· Medical tutorials
· Related forum posts
· Related articles
· Related downloads
· Submit article
· Ophthalmology alerts
· Ophthalmology books
· Ophthalmology past papers


Most read story about Ophthalmology:
Leucocoria



Server Status: 108 pages served in last minute. Page generation time: 0.072 seconds

Site Maps: [Books] [News] [Forums] [Reviews] [Mnemonics]

sitemap - top30 - centuries - testimonials


About Us :: Disclaimer :: Contact Us :: Reporting abuse :: Terms of Services :: Privacy Policy

Advertise with RxPG!
Made in India by RxPG Medical Solutions Private Limited

"RxPG" is a Registered Trademark

Chrome Web Store YouTube Twitter LinkedIn Wikipedia Facebook