Here are few prognostic factors for Ca cervix:
Those presenting at less than 35 yrs of age have WORSE prognosis!
THE OLDER THE BETTER.
The more advanced the stage the poorer the prognosis is!
3)GRADING AND TYPING:
4 types of grades and types are observed:
1)Large cell keratinizing type
2)Large cell non keratinizing type
3)Small cell keratinizing type
4)Small cell non keratinizing type
LARGE CELL KERATINIZING TYPE HAS THE MOST FAVOURABLE PROGNOSIS
4)Lymph & Vascular space Invasion(LVSI):
this denotes the microscopic involvment of capillaries and lymph vessels by tumour cells.
LVSI is always associated with worse prognosis and stormy progression from a lower stage to the higher ones.
5)DEPTH OF INVASION and LYMPH NODE involvment:
5mm depth----------2% lymph nodes involved
6-10mm depth------5% lymph nodes involved
>15mm depth------26% lymph nodes invloved
6)Occult parametrial extension:
occult parametrial involvment in the form of any change in form or consistency of the parametrium is associated with worse prognosis.
7)Tumour size and volume:
large tumours have worse prognosis than small tumours,though in the same stage!
thus a 1cm stage I has a better prognosis than a 6cm stage I tumour.
decreased immunity is associated with higher risk for invasive carcinoma and again stormy progression.
thus,an AIDS pt. with a low CD 4 count has a worse prognosis than an otherwise normal female,with Ca cervix,though in the same stage.
happy studying all of u!