---

1) In the case of a fifty year old man with a phaeochromocytoma:

Choose 2 of the following options.

   1. The administration of glucagon will elevate his plasma catecholamine levels.

   2. The administration of clonidine will suppress his plasma catecholamine levels.

   3. I-131 - metaiodobenzyl guanidine can be used to localise the site of his tumour.

   4. There is a less than 1% chance that the tumour is malignant.

   5. None of the above

---

2) With regard to the Dandy-Walker syndrome:

Choose 4 of the following options.

   1. The cerebellar vermis is hypoplastic.

   2. Obstructive hydrocephalus is the commonest mode of presentation.

   3. Presentation usually occurs within the 1st two years of life.

   4. A cyst is always present in the posterior fossa

   5. Death occurs in first ten years of life

---

3) In transfusion practice:

Choose 4 of the following options.

   1. Fever is usually due to anti-leucocyte antibodies

   2. Desmopressin (DDAVP) will raise levels of factor VIII in patients with mild haemophilia A

   3. Haemolytic reactions may be delayed for up to 1 week

   4. Severe anaphylaxis may be seen in IgA deficient individuals

   5. None of the above

---

4) Recognised causes of macrocytosis in the peripheral blood with normoblastic erythropoiesis in the bone marrow include:

Choose 3 of the following options.

   1. Hypothyroidism

   2. Chronic alcohol abuse

   3. Cryptogenic cirrhosis

   4. The administration of phenytoin

   5. The administration of valproate

---

5) Which are true of Hepatitis E virus?

Choose 2 of the following options.

   1, It is a 34nm single stranded RNA virus.

   2. It is more common in IV drug abusers

   3. Can produce epidemic waterborne infections

   4. Will cause 10% of patients to develop chronic hepatitis

   5. All of the above

---

6) Which of the following are correctly paired?

Choose 4 of the following options.

   1. Conn's syndrome and metabolic alkalosis

   2. Uretero-colic anastomosis and hyperchloraemic acidosis

   3. Shock and metabolic acidosis

   4. Cushing's Syndrome and Normokalemia

   5. Pancreatic fistula and metabolic acidosis

---

7) The following are recognised causes of pulmonary fibrosis:

Choose 3 of the following options.

   1. External raditaion for carcinoma of the breast

   2. Bleomycin

   3. Sarcoidosis

   4. Myelofibrosis

   5. None of the Above

---

8) Recognised causes of finger clubbing include:

Choose 2 of the following options.

   1. Carcinoid tumour

   2. Bronchial carcinoma

   3. Iron deficiency anaemia

   4. Coeliac disease

   5. Folate Deficiency

---

9) Dupuytren's contracture has a recognised association with:

Choose 4 of the following options.

   1. Diabetes Mellitus

   2. Peyronie's disease

   3. Epilepsy

   4. Alcoholic liver cirrhosis

   5. Acromegaly

---

10) In the treatment of chronic hepatitis B virus:

Choose 2 of the following options.

   1. Corticosteroids are always beneficial

   2. 40% of patients can be expected to respond to interferon

   3. Combined treatment with acyclovir and interferon is more effective than interferon alone

   4. Interferon can be associated with a rise in transaminases towards the end of therapy

   5. None of the above