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Answer Key to TNPSC 11th October 2003; Version 1.02

Author: Bruno, Posted on Wednesday, October 15 @ 12:21:26 IST by rxpg  

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TNPSC


1.Excessive bleeding from birth canal and uterus in amniotic fluid embolism is due to -- D.DIC
2.Splenic infarct – Pale infarct
3.Wound healing by replacement of fibrous tissue is—repair
4.Commonest benign tumour of salivary gland is—Pleomorphic salivary adenoma
5.Under normal conditions rigor mortis develops—within 4-8 hrs


6.commonest histologic type of lung cancer is—Adenocarcinoma( Harrison says-“ In the past 25 years, for unknown reasons, adenocarcinoma has replaced squamous cell carcinoma as the most frequent histologic subtype for all sexes and races combined”)
7.Ballooning degeneration is a feature of—Acute viral hepatitis
8.Mental retardation is a characteristic feature of—Trisomy 21
9.Most common cause of primary hyperparathyroidism—parathyroid adenoma
10.In shock,the renal changes are—Acute tubular necrosis
11.Acid base disturbance met in diabetic ketoacidosis—metabolic acidosis
12.All of the following substances have been used to estimate GFR except—Phenol red(Inulin,creatinine-well known,mannitol is also used-refer Gutyon page 307.Phenol red is used for assessment of tubular function.)
13.Nephrotic syndrome is characterized by all except—Serum cholesterol level is below 150 mg/dl
14.normal level of inorganic phosphate in plasma of a normal adult is—3-4 mg/dl
15.Hypokalemic Acidosis with normal anion gap occurs in all, except—Renal failure
16.IN PROTEIN BOUND IODINE,THE SUBSTANCE WHICH IS BOUND TO PROTEIN IS--Iodine
17.Sodium level in serum is increased in—Cushing’s syndrome
18.The most sensitive diagnostic enzyme for hepatic jaundice is—SGPT
19.Elevation of the following houmone occurs in pheochromocytoma—catecholamine
20.Vanden bergh test is biphasic in – hepatocellular jaundice
21.Fetal hemoglobin—Disappears from circulation after birth
22.ELEVATED T 4 , LOWERED T 3 UPTAKE TOGETHER SUGGEST THE LIKELIHOOD OF Increases TBG
23.Catecholamine brings immediate hyperglycemic effect by the following processed except—inhibiting uptake of amino acids
24.Cushing’s syndrome is characterised by the following features, except—Decrease in cardiac size
25.The vehicle of transport of triacyl glycerol from the liver to extrahepatic tissues is—VLDL
26.Prostaglandins are liberated in the circulation by the stimulation of—Adrenal gland (Harper 254 )
27.The concentration of sphingomyelins is increased in—Niemann-pick disease
28.Refsum’s disease is due to the defect in the following type of oxidation in fatty acid—Alpha
29.SERUM SODIUM AND POTASSIUM ARE ESTIMATED USING THE FOLLOWING TECHNIQUE—Flame Photometry
30.Milk is rich in all the following except—Iron
31.The initial thromboplastin for clotting comes from—Damaged vessel wall and surrounding tissues.
32.First degree heart block is identified in the ECG by—prolonged P-R interval
33.The physiological split of the second heart sound is better heard during—inspiration(Hutchison 175)
34.Marey’s law states—heart rate is inversely proportional to blood pressure(Chauduri physiology page 232)
35.Inspiration is characterised by all, except—increased arterial pressure
36.normal ventilation perfusion ratio is—0.8
37.O2 therapy in NOT useful in the following conditions except—Pulmonary oedema
38.As urine enters collecting duct, it is-- Hypotonic or Isotonic, but never hypertonic
39.Hypernatremia can cause he following except—cessation of ADH release from posterior pituitary
40.Pineal gland is the chief source of—Melatonin
41.Prodrug is – inactive drug which gets activated in body
42.Therapeutic index of a drug—Denotes its margin of safety
43.All of the following drugs are microsomal enzyme inducers, except—cimetidine
44.When the rate of elimination is derectly proportional to drug concentration, it is—First order kinetics
45.The following general anaesthetics sensitise the myocardium to epinephrin, except—Diethyl ether
46.Drug combination which produces neuroleptanalgesia is—Droperidol + Fentanyl
47.Drug of choice to prolong the duration of action of xylocaine is—Epinephrin
48.SPINAL ANAESTHESIA MAY GIVE RISE TO THE FOLLOWING SIDE EFFECTS EXCEPT Hepatic Failure
49.One of the following drugs produces dissociative anaesthesia—ketamine
50.Protamine sulphate reverses the effect of one of the folloing agents—heparin
51.Anterior pituitary gland exerts very little control on the regulation of secretion of—Adrenaline
52.Thyroxine is stored in the thyroid gland in the form of—Thyroglobulin
53.Calcium absorption in the small intestine in increased by—1-25 Dihydroxy cholecalciferol
54.During normal menstrual cycle, omulation occurs as a result of—Surge of LH
55.Failure of the testis to descend(Cryptorchidism) – makes it more prone to malignant change
56.Loss of liver function tends to cause all except—A rise in the plasma urea level
57.Duchenne’s muscular dystrophy, a conginital muscular disorder due to the absence of muscle protein—Dystrophin
58.In sensory aphasia – Wernick’s area is damaged
59.which one of the following is not the extrapyramidal tract—Corticospinal
60.A patient shows involuntary athetoid movements.He probably has—lesion in basal ganglion.
61.Name the drug used for increasing breast milk secretion—metoclopramide
62.What complication will you suspect when a child with diarrhoeal dehydration develops hypotonia and paucity of limb movements—Hypokalaemia
63.What vaccine is specifically recommended for children with nephrotic syndrome—Pneumococcal vaccine
64.What is the most likely diagnosis when a neonate has respiratory distress,Scaphoid abdomen and a dextroposed heart—Diaphragmatic hernia
65.Malignant pustule is caused by—B.anthrax
66.Investigation of choice to demonstrate VUR is—Contrast MCU
67.When a patient with a history of fall presents days later with headache and progressive neurological deterioration the diagnosis is—Chronic subdural haematome
68.Appendicectomy is not advised in—Crohns
69.Tardy Ulnar palsy is due to—Fracture of Lateral Epicondyle of humerus leads to Tardy Palsy, ONLY WHEN THE COMPLICATION IS CUBITAL VALGUS. Withoit Cubital Valgus (cubitus valgus is but one complication of a Malunited #) there is no Palsy
70.Klippel geil syndrome is due to—congenital agenesis of one or more cervical spine
71.Common cause of Kussmaul’s sign is—constrictive pericarditis
72.The commonly recommended investigation to detect and study the arterial insufficiency of a limb is—Doppler Duplex imaging
73.Which of the following personality disorders has been linked to alcoholism in relatives—Antisocial
74.What is the major area of Brain implicated in Alzheimer’s disease and Amnestic disorders—Hippocampus
75.All of the following statements about Delirium are true, except—it usually resolves without treatment (Neeraj Ahuja 19)
76.Choose the nonatherogenic lipoprotein—HDL
77.Down’s syndrome babies die of—all of the above(accidents,cardiac failure, AML)
78.Strider in infancy is due to—Acute laryngotracheal bronchitis
79.Milk feeds are contraindicated in—All of these (Galactosemia, Phenylketonuria, Hereditary lactose intolerance)
80.Which drug is rsed in the treatment of neurocysticercosis—Albendazole
81.The following agents are used in Acute Myocardial Infarction, except—Antifibrinolytics
82.Gingival hyperplasia is a side effect of—Diphenyl hydantoin
83.The safest tetracycline for extra0renal infection in a patient with renal failure is—Doxycycline
84.The vitamin given for prophylaxis of isoniazid induced peripheral neuritis—pyridoxine
85.Quinidine is contraindicated in—Digitalis toxicity
86.All of the following drugs are used in hypertensive emergencies, except == Thiazide
87.THE BETA BLOCKER WITH LOCAL ANESTHETIC EFFECT IS-Pindolol Refer Katsung – The table on beta blockers
88.Rebound hypertension is seen with—Clonidine
89.Which of the following drugs is used to dissolve gall bladder stone—Chenodeoxycholic acid
90.Which of the following drugs is not an antitussive—meperidine
91.The umbilical cord contains—one vein and two arteries
92.The following cardiovascular changes take place in pregnancy, except—increase in systolic blood pressure
93.PHOBIAS WOULD BE LEAST LIKELY TO OCCUR IN CONJUNCTION WITH OR AS MANIFESTATION OF WHICH OF THE FOLLOWING DISORDERS—ANOREXIA NERVOSA?????????
94.All the following statements about Hyperventilation syndrome are true, except—it may lead to respiratory acidosis
95.Normal pressure hydrocephalus is usually associated with dementia, gait disturbance and -- urinary incontinence.
96.WHICH OF THE FOLLOWING DISORDERS HAS MOST FREQUENT POSITIVE FAMILY HISTORY—BIPOLAR DISORDER???????
97.Adverse effects following Ganja use include all of the following except—Bradycardia(Harrison 14th 2514)
98.Drug of choice in delirium tremens is – Diazepam
99.The plane of clevage of dissecting aneurysm of Aorta is—along tunica media (Davidson 275)
100.Red coloured Urine in porphyria is due to—PBG, ALA, Protoporphyrin ????



101.Adherence of neutrophil and monocyte to the vascular endothelium prior to movement into extravascular compartment is called—Margination
102.Mallory body is seen in the following except—yellow fever(opghai 262,Robbins 869)
103.Ig A is mostly synthesized by—Payer’s patches of small intestine
104.LYMPHOMAS ARE MONOCLONAL ONLY.THIS CAN BE DETECTED BY Isoenzyme markers and Clonal Rearrangements – Harrison
105.Ulcerative lesions in typhoid fever in intestine are—longitudinal ulcers
106.Which of the following markers is associated with placental trophoblastic tumour—Human placental lactogen (Robbins 1089)
107.Exfoliative cytology is useful for the diagnosis of—Cervical cancer
108.The first malignancy in which cancer suppressor gene was discovered is – Retinoblastoma
109.The tumour suppressor gene is—p-53
110.The following are mainly intracellular parasites, except—Echincoccus granulosus
111.RH NEGATIVE MOTHER SHOULD RECEIVE ANTI-D GAMMAGLOBULIN AFTER DELIVERY IF—BABY RH POSITIVE AND COOMB’S Negative.



The paper setter has mentioned that the baby is Rh Positive and Coomb’s Negative. That means it is Direct coomb’s test that is done on the baby. That means that there is no antibodies in the mother’s blood and she has to be given Immunoglobulin. Id the baby is Coomb’s positive, then the mother ALREADY at present as Antibodies and Anti D is not useful
112.Placenta praevia is diagnosed by – Ultrasonogram
113.The common clinical syndrome in schizophrenia includes all except—memory loss
114.DELUSIONS ARE NOT FOUND IN—PERSONALITY DISORDER???????????
115.Neurological properties of antipsychotic drugs include all except—Anticonvulsant
116.Electroconvulsive therapy is most effective in the treatment of—Depressive disorder(Davidson 987)
117.Audiological evaluation is necessary under the following conditions, except in—Birth weight more than 3 kg (OPG 334)
118.Turner syndrome is associated with – Coarctation of aorta
119.The following is the clinical hallmark of classical haemophilia—Hemarthrosis
120.Couvelaire uterus is diagnosed by—Laparotomy
121.WHO was established in—1948
122.matched:
papaya- vit A,soya beans- protein, ragi—calcium, amla fruit—vit c (i.e.choice A)
123.Salk vaccine is a – Killed vaccine
124.THE COMMONEST MODE OF TRANSMISSION OF AIDS IN INDIA—HETERO,HOMO,TRANSPLACENTAL???????????
125.Conventional contraceptives include one of the following—condom
126.In which stage of the demographic cycle is India—late expanding
127.Framingham heart study—cohort study
128.Hundred day cough is the name of—Bordetella pertussis
129.If the birth weight is 3 kg, by the end of one year of age, it should become—9 kg
130.PQLI considers-expectancy at one,IMR,literacy rate (ans is choice D)
131.The most common presentation in anencephaly is—Face
132.Encirclage operation stitch should be removed—at 38 weeks (Dutta 184)
133.Congenital atresia of the lower genital tract may cause—Cryptomenorrhoea
134.Treatment of choice for chorio carcinoma is—Methotrexate
135.Greenish vaginal discharge with severe itching is due to—Trichomoniasis
136.Clue cells—Haemophilus vaginalis vaginitis
137.The regional lymph node to the ovary is—Para aortic
138.the ratio of weight of mature placenta to that of the foetus at term is—1:6
139.Following are the sampling technipues used to conduct community health surveys, except—. Refer Mahajan and Bhaskar Rao
140.Which of the following is primordial prevention—Prevention of emergence of development of risk factors
141.The following are the boundaries of Douglas pouch, except—Laterally sacrogenital folds(Refer chaurasia vol II p.204)
142.The following are the branches of superior mesentric artery except—Left colic
143.In aneuploidy, there is-Non disjunction in a meiotic division ( refer Davidson)
144.The main pancreatic duct is formed from—Choice B – In Gray and Embryology Dutta – (Mcgregor !!!)
145.The bursae that are affected when a person kneels for a long time are—Subcutaneous infrapatellar bursae
146.In human embryo, the yolk sac is a source of—Primordial germ cells. But Gray says Blood Cells !!!

147.Following are the main characters of large intestine, except—villi
148.the lining epithelium of trachea is—pseudo stratified ciliated epithelium
149.The right bronchus – Short,straight
150.ALL OF THE FOLLOWING WILL SUPPORT THE HEART AND KEEP IN POSITION EXCEPT—LIGAMENTS OF VERTEBRAL COLUMN???????

151.Stave cells are present in—spleen
152.parasympathetic component is present in all, except—Trochlear nerve
153.left gonadal vein drains into—left renal vein
154.Herringbone pattern of the duct system is seen in—pancreas
155.Charcot’s srtery of cerebral haemorrhage is a branch of—middle cerebral
156.The commonest type of vermiform appendix is—retrocaecal
157.Coracoid process is an example for—atavistic epiphysis
158.Division of centromere perpendicular to the long axis of the chromosome results in—isochromosome
159.Chemical that arrests the cell division at metaphase stage is—Colchicine
160.Chromosomal configuration in klinefelter’s syndrome is—47 XXY
161.the freshly prepared ORS should not be used after—24 hours
162.WHO defines anaemia in pregnancy an Gb less than – 11 g%
163.Foeto maternal transfusion detected by—Kleihauser’s test
164.In carcinoma of cervix with spread to lateral pelvic walls, Treatment of choice is—radiotherapy Referene Please
165.least common complication of fibroid is—malignancy
166.uncommon cause of infertility in female is—mycoplasma(shaw 160)
167.INSULIN REQUIREMENT IN A PREGNANT DIABETIC WOMAN IS DECREASED IN--?HYPEREMESIS GRAVIDARUM ? Exercise
168.IRON PROPHYLAXIS IN A PREGNANT WOMAN IS STARTED AT—16TH /20th WEEK
169.Carcinoma cervix may be caused by—papilloma virus
170.The most common cause of hypofibrinogenaemia is – abruptio placentae / septic Abortion/ IUD
171.Conditions in which obesity is an associated feature include all except—Grave’s disease
172.Diarrhoea is a manifestation in the following conditions except—myxoedema
173.causes of dark coloured urine are—all of these(haemoglobinuria,alkaptonuria,methemoglobinuria)
174.All are associated with massive proteinuria,except—polycystic kidney
175.Causes of exudative pleural effusion include all except—pulmonary infarction
/ Pneumonia / Meigs / Ca Bronchus
176.Incorrect about ARDS is—high Pulmonary capillary pressure ( In fact there is increased leakage from capillaries in ARDS )
177.Wolff-parkinson white syndrome is characterised by all except—prolonged pr interval
178.All are true in DIC except—platelet count increased
179.Sullage consists of—waste water from kitchen
180.the systematic study of human disease and social factors is—social medicine ????
181.Concentric diminution of vision ( Tunnel vision ) occurs in—all of these(Glaucoma,l retinal diseases ,papilloedema progressing to optic atrophy)
182.Myasthenia gravis is associated with—Serum acetyl choline antibodies
183.What is true of vitamin k—all are true
184.ketoacidosis occurs in—all of these(diabetes,alcoholism,starvation)
185.Ascitis precox occurs in—constrictive pericarditis
186.ST depression in ecg occur in—all of these
187.massive haemoptysis with chest pain occurs in—pulmonary infarction
188.The earliest manifestation of Sheehan’s syndrome is—failure of lactation(Harrison p 1993)
189.Neuromuscular causes of dysphagia are the following except—histoplasmosis
190.THYROID MYXOEDEMA CAN BE DIFFERENTIATED FROM PITUITARY MYXOEDEMA BY THE EXAMINATION OF ?? Axillary Hair
191.Cavernous sinus thrombosis is differntiated from orbital cellulitis by—both eyes involved (Rao 215)
192.Coronary arteries perfuse the following, except—endocardium
193.Bennet’s fracture dislocation is of base of—first metacarpal
194.when the wound is badly contaminated with dirt and organic material, which of the following should be done—debridement
195.which of the factors is the best guideline to assess the prognosis in breast cancer—size of the tumour and nodal status
196.scleroderma commonly involves—oesophagus
197.HIGH LACTOFERRIN LEVEL IN PANCREATIC JUICE IS FOUND IN-Chronic Pancreatitis. Refer Oxford Text book of Surgery
198.the most common cause for the oral cancer is—usage of tobacco
199.Haemorrhagic fever is associated with the following viral infections, except—parvovirus infection
200.All contribute to atherosclerosis, except
-- consumption of sea foods<



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