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Pharmacology; Free Online Mock Test 137 (DNB & FMGE Pattern)

Author: RxPG, Posted on Tuesday, January 06 @ 14:46:05 IST by RxPG  

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DNB Part 1

Multiple Choice Test



1) Drug delivery method LEAST suitable for long term (days to weeks) slow release.

One answer only.
pellet implant under the skin (subcutaneous)
time release capsule
i.m. injection of a drug-oil suspension
transdermal patch





2) Most drug have molecular weights between:

One answer only.
10 - 100
100 and 1000
7 - about 60000
above 60000



3) Drug-transport system described as "energy requiring":

One answer only.
glomerular filtration
facilitated diffusion
active transport
B & C



4) General term having to do with actions of the body on the drug:

One answer only.
pharmacodynamics
pharmacogenetics
pharmacokinetics
absorption



5) Term having to do with drug actions on the body:

One answer only.
pharmacokinetics
pharmacodynamics
pharmacogenetics
placebo



6) Mechanism(s) of drug permeation:

One answer only.
aqueous diffusion
use of carrier molecules
endocytosis and exocytosis
all of the above



7) Example(s) of covalent drug-receptor interactions:

One answer only.
activated phenoxybenzamine-receptor
anti-cancer DNA alkylating drugs, like cyclophosphamide (Cytoxan)
norepinephrine
A & B



8) Weak organic acid, pKa 6.5. Percent ionization at pH 7.5

One answer only.
1%
10%
50%
90%



9) Most common mechanism of drug permeation:

One answer only.
endocytosis
carrier-mediated transport
active-transport
passive diffusion



10) Dramatic decrease in systemic availability of a drug following oral administration is most likely due to:

One answer only.
extreme drug instability at stomach pH
hepatic "first-pass" effect
drug metabolized by gut flora
patient non-complance


The questions of this test and the other problems about DNB test can be discussed in DNB Forum




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