RxPG - the perfect Rx for medical Post Graduate entrance blues!
Mobile Edition | Help/Newbie? | 24/7 Support
HOT | PrePG | MCQ | DNB | Careers | Books | Colleges | Dental | DocIndia | PLAB |  USMLE  | Australia | Canada | GLOBAL | OffBeat!
Articles | Forums | MCQ Crammer | Downloads | Mnemonics | Revision Tools | Recent Shouts | All Features

Congenital adrenal hyperplasia

Author: medicol, Posted on Wednesday, April 14 @ 07:35:47 IST by RxPG  

 FRIEND Add to My Pages   PRINTER Printer Friendly   FRIEND Email Story  FRIEND Download Story  Medicine alerts 


Like all congenital conditions, this appears at birth and is an enlargement of the adrenal glands, which sit just above the kidney. They produce hormones that control the growth of the body, the development of sex organs and the way the body reacts to stress.


Congenital adrenal hyperplasia is sometimes called the adrenogenital syndrome. Infant boys or girls suffer an early onset of male puberty, with an enlarged penis in the boys, a large clitoris in girls and facial hair in both. The body grows rapidly, but at too early a stage the bones stop growing and normal height is not reached.


The basic cause is a genetic defect that prevents the adrenal glands from manufacturing the steroid hormone cortisol. The low level of steroids in the blood causes a gland in the brain (the pituitary) to produce large quantities of a hormone to try to stimulate the adrenal glands to produce more cortisol. Instead, they can only produce large quantities of the male sex hormone.


A diagnosis is made on the basis of how the body looks and the measured levels of hormones in the blood.


Congenital adrenal hyperplasia can be effectively treated by regular doses of the drug hydrocortisone. This is identical to the natural steroid cortisol produced by the adrenal glands, and the presence of it in the blood immediately stops the pituitary gland from sending out too much of its own hormones. Hydrocortisone, or another steroid drug, is given by injection to infants, but later in life can be taken in tablet form by mouth.

In girls, surgery may be necessary along with treatment with hydrocortisone to restore a feminine appearance. Normal menstrual periods and even pregnancy may be possible. In boys, hydrocortisone suppresses the excess male hormone production and allows a normal puberty to occur at the right time.


Because of its genetic origin, the condition cannot yet be prevented, but it is possible to have advice about future pregnancies and how to prevent it happening again.

4 (Excellent) 3(Good) 2(Good) 1(Bad)   

Recommended Books for Medicine
• Books to read for Medicine by RxPG

Related Medicine articles
• Types of Tongues in Various Medical Conditions
• Signs in Meningitis
• How To Read Harrison And Make The Most Of It?
• Examination of nails in medicine
• Triads in Medicine: A Quick Revision List
• Medical Conditions affecting Nails
• Diagnosis of diffuse lung disease
• Common simple emergencies
• Wilson's disease
• medicine updates!
• Abnormal colours of urine
• Noonan's syndrome
• Medicine; Online Mock Test (PGI Pattern)
• Characteristic Feature of Hypocalcaemia
• diagnosis of pulmonary microembolism.
• Differentiating features of Leukemias (Leukaemias)

Related Medicine Discussions

Other articles by medicol
• Congenital adrenal hyperplasia

 Medicine FAQ
  Browse all FAQs

Write an Article on Medicine
You can share your exam experiences, preparation strategies, books you have read or just any information about Medicine on RxPG website and we will publish it under your name.

Article Rating
Average Score: 3.5
Votes: 2

Most Read Article
How To Read Harrison And Make The Most Of It?

Related Links
· MRCP books at Amazon.com
· Clinical Skills
· Medicine Books at Amazon.com
· Medicine Forum
· Discuss Past Papers
· Harrison's Free Trial


· Medicine section
· Articles by medicol
· Add to my pages
· Printer friendly version
· PDF version
· Email article
· Feedback on this article
· Medical tutorials
· Related forum posts
· Related articles
· Related downloads
· Submit article
· Medicine alerts
· Medicine books
· Medicine past papers

Most read story about Medicine:
How To Read Harrison And Make The Most Of It?

Server Status: 93 pages served in last minute. Page generation time: 0.042 seconds

Site Maps: [Books] [News] [Forums] [Reviews] [Mnemonics]

sitemap - top30 - centuries - testimonials

About Us :: Disclaimer :: Contact Us :: Reporting abuse :: Terms of Services :: Privacy Policy

Advertise with RxPG!
Made in India by RxPG Medical Solutions Private Limited

"RxPG" is a Registered Trademark

Chrome Web Store YouTube Twitter LinkedIn Wikipedia Facebook