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Clopidogrel - The Super Aspirin
by wikipedia - 1000 reads, based on 3 votes
Clopidogrel is a potent oral antiplatelet agent often used in the treatment of coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
Pharmacology
The mechanism of action of clopidogrel is irreversible inhibition of the adenosine diphosphate (ADP) receptor of platelet cell membranes. This prevents aggregation of platelets....
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Digoxin - Cardiac Glycoside from Foxglove Plant
by wikipedia - 1169 reads, based on 1 vote
Digoxin is a cardiac glycoside extracted from the foxglove plant, digitalis. It is widely used in the treatment of various heart conditions, and has two distinct actions on the heart.
Digoxin inhibits the Na+-K+ ATPase pump in the membranes of the heart cells (myocytes). This causes an increase in the level of sodium ions in the myocytes, which then leads to a rise in the level of calcium ions. This increased level of calcium increases the contractility of the myocardium (muscle of the heart)....
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Abciximab - A Platelet Aggregation Inhibitor
by wikipedia - 1209 reads, based on 2 votes
Abciximab (previously known as c7E3 Fab), manufactured by Centocor and distributed by Eli Lilly under the trade name ReoProŽ, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. Its mechanism of action is inhibition of glycoprotein IIb/IIIa....
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