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Coumadin Skin Necrosis
by Tappi - 1517 reads, based on 2 votes
Coumadin Skin Necrosis: Clinical Manifestations One or more well-circumscribed areas of painful edema with peau d'orange appearance typically appear over areas of subcutaneous fat deposition, such as buttocks, thighs, abdomen, and breasts. Petechiae, ecchymosis, and irregular necrosis with an erythematous halo subsequently appear in these sites, followed rapidly by the development of hemorrhagic bullae. Necrotic areas may slough with formation of deep ulcerations. ... More

Stevens-Johnson Syndrome
by Tappi - 1947 reads, based on 2 votes
Clinical Manifestations 1. Dusky plaques with necrosis often involve the trunk, face, and extremities. 2. These lesions may be painful. 3. Erosions or bullae cover ... More


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