Page 1 of 1: prolong Q-T Syndrome

dr2005 · Credits: 395 My Scrapbook

Which of the following are known to prolong the QT interval?
A-Amitryptyline
B-Digoxin
C-Hypocalcemia
D-Hypokalemia
E- Hypocalcemia

BRAVO · Credits: 45704 My Scrapbook

Hypocalcemia
hyperkalaemia

dr2005 · Credits: 395 My Scrapbook

how about Amitryptyline ?

naseem · Credits: 1447 My Scrapbook

hypocalcemia and hypokalemia digoxin prolongs PRinterval not QT

drkbravva · Credits: 24026 My Scrapbook My Reading List 1 Books

Prolonged QT
See Also
Prolonged QT
Torsades de Pointes

Risk Factors for Medication-Induced Torsades de Pointes
Female gender
Hypokalemia
Severe Hypomagnesemia
Bradycardia
Atrial Fibrillation Cardioversion recently
Congestive Heart Failure
Concurrent Digoxin use
Baseline QT Prolongation or subclinical long QT

Medications causing Torsades de Pointes
General
Higher doses of predisposing drug raise risk
Rapid drug administration raises risk
Medications that more commonly cause Torsades
Bepridil
Disopyramide
Dofetilide
Ibutilide
Procainamide
Quinidine
Sotalol

See Prolonged QT Interval due to Medication
Familial long QT Syndrome
Congestive Heart Failure
Myocardial Infarction
Hypocalcemia
Hypomagnesemia
Type I Antiarrhythmic drugs
Rheumatic Fever
Myocarditis
Congenital Heart Disease

Congenital LQTS is usually inherited. It is caused by an abnormality in the gene that forms the ion channels, slowing the recovery phase of the heartbeat. Forms of inherited LQTS include:

Recent Classifications – LQT1, LQT2, LQT3, LQT4, LQT5; these are classified by the type of channel which causes the LQTS. The type of LQTS classification is related to the risk of future cardiac events, those with LQT3 having the highest risk of life-threatening arrhythmias.
Jervell, Lange-Nielsen Syndrome – both parents are carriers of the abnormal gene, but they do not have LQTS. Each child has a 25-percent chance of inheriting LQTS. This syndrome is associated with deafness at birth and is extremely rare, as there is a small chance that both parents would carry the LQTS gene.
Romano-Ward Syndrome – one parent has LQTS and the other parent does not. Each child has a 50-percent chance of inheriting the abnormal gene. In this syndrome, hearing is normal; however the likelihood that children in this family would have LQTS is greater. The gene may be present in all the couple’s children, some of them or none at all

Romano-Ward syndrome is an autosomal dominantly inherited form of long QT interval and there is a risk of recurrent ventricular tachycardia, particularly Torsade de Pointes.

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& others

drnikki · Credits: 120 My Scrapbook

agree....hypocalcemia

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