Page 1 of 1: physiology -paneth cells

kannan · Credits: 6918 My Scrapbook

paneth cells in the mucosa of small intestine secrete
a]lysozyme
b]bioactive peptides and amines
c]pepsin and renin
d]bicarbonate

b??

BRAVO · Credits: 45736 My Scrapbook

lysozyme

docvin · Credits: 1662 My Scrapbook

rt.....

kalika · Credits: 12507 My Scrapbook My Reading List 12 Books

Paneth cells are found in the small intestine but not in the large intestine.

It's recently been shown that the granules contain a form of bactericide, and lysozyme-like agents.

This suggests they're responsible for protecting the gut against bacterial overgrowth

They can be seen in H&E preparations, but the PAS routine makes them really stand out.

The granules of Paneth cells are much coarser and more obvious than those of enteroendocrine cells.

The cells are usually found clustered in groups of three to six or so, and in this image you see a cluster of them, located (as they tend to be) at the very deepest part of an intestinal crypt.

They aren't endocrine cells, although they often are located in the same vicinity.

Unlike the endocrine cells' products, the secretions of the Paneth cells are relased into the lumen of the intestine.

DrJayKill · Credits: 2554 My Scrapbook

r lysozymes peptides?

DrJayKill · Credits: 2554 My Scrapbook

r they bactericidal or bacteriostatic?

decembermist · Credits: 41191 My Scrapbook

I thnk they are peptides - and bactericidal in action !!

Pls do correct me if Im wrong !!

docsa · Credits: 9053 My Scrapbook

lysozymes

A number of lysozymes are found in nature; in human tears and egg white, for examples.

ThIS enzyme is antibacterial because it degrades the polysaccharide that is found in the cell walls of many bacteria. It does this by catalyzing the insertion of a water molecule

docsa · Credits: 9053 My Scrapbook

Most of the bacteria affected by lysozyme are not pathogenic. It could be argued that lysozyme is a primary reason these organisms did not develop pathogenic strains...

Lysozyme serves as an unspecific innate opsonin by binding to the bacterial surface to reduce the negative charge and facilitate phagocytosis of this bacterium before opsonins from the acquired immune systems enter the scene.

The enzyme functions by attacking peptidoglycans and hydrolyzing the bond that connects N-acetylmuramic acid with the fourth carbon atom of N-acetylglucosamine.

THIS MEANS THEY SHUD BE CIDAL IN ACTION

DrJayKill · Credits: 2554 My Scrapbook

if lysozymes are indeed peptides then most appropriate answer to the above question should be B coz paneth cells also release substances like alpha defensins... unfortuanately i dont remember their function though.

		Sign In New User? Sign Up Sign in to access your control panel and messenger!
				TechZone \| SpiderNevi \| HowTo? \| Scrapbook!