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WHICH VIT IS COMPONENT OF WARBURG YELLOW ENZYME
A B1
B B2 .....a?
C NIACIN
D PANTOTHENIC ACID
WHAT IS THIS WARBURG YELLOW ENZYME?

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NADPH dehydrogenase
It is a flavoprotein that reversibly oxidises NADPH to NADP and a reduced acceptor. Warburg won the Nobel Prize in Physiology or medicine in 1931 "for his discovery of the nature and mode of action of the respiratory enzyme."

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vit b2

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vit B2

Warburg's yellow enzyme: A key respiratory enzyme discovered by the German biochemist Otto Heinrich Warburg (1883-1970), a pioneer in research on the respiration of cells and the metabolism of tumors. Warburg's yellow enzyme is a flavoprotein that catalyzes an oxidation-reduction reaction. This reaction is necessary for the cells to normally breathe (respire).

Warburg won the Nobel Prize in Physiology or medicine in 1931 "for his discovery of the nature and mode of action of the respiratory enzyme."

The rank that they possess as catalysts is dependent on the velocity of the hydrogen-transportation and the degree of the activation of the hydrogen - problems that still await a satisfactory solution. On the other hand, Hugo Theorell succeeded in 1934 in isolating, in Warburg's laboratory, the first really rapid hydrogen-transporter, called «the yellow enzyme». He could also show that it was a phosphoric-acid ester of vitamin B2, linked to a specific protein. Warburg and Christian, in 1935, defined the nature of the active group in two other dehydrogenases, colourless and metal-free (co-ferment and co-zymase), which had long frustrated the attempts of other investigators. One of them was the catalyst that Szent-Györgyi had placed in this section of the oxidation-chain.

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