Page 1 of 1: AIDS AND organ transplant

ratnakar_potla · Credits: 5703 My Scrapbook My Reading List 2 Books

Is a patient with AIDS not eligible to donate kidney to a normal recipient in dire need assuming ESRD. Lets start with a newly diagnosed AIDS patient as donor.
what are risks to recipient?
what are risks to donor?
is it not feasible to proceed as we opt for iatrogenic AIDS like state i.e immunosuppression post surgery?

drlouis · Credits: 5374 My Scrapbook

there are many things involved in this...

1)ethical issue-the fear and stigma of receiving kidney donation from a hiv pt(eventhough its confedential)
2)medical reasons-u can`t completely clean a organ free from viral particles from a AIDS pt.(when we know that exposing oneself to blood and blood related products from hiv positive individual can lead to infection)
3) a whole lot of other bacteremia and transmissible infections like cmv,hcv and what not ---are likely--which can complicate the post-taransplant infection and rejection
4) although immunosuppression is helpful in preventing rejection(as seen in some aids pts unable to reject)---this mode is clearly not desirable and pt can die of other oppurtunistic infection and malignanacy quickly rather than renal failure -if at all
5) for the donor-usual morbidities as a non-infected individual with some extra complications--afterall he has already lost the soul and meaning of life (depression and social rejection) that he may not bother with the lost kidney!

dr.robert.

ratnakar_potla · Credits: 5703 My Scrapbook My Reading List 2 Books

dONT YOU THINK dR.ROBERT that instead of giving immunosupression drugs which all invariably lead to increased risk of opportunistic infections ....... a patient with ESRD be given a transplant from hiv patient and leave him happy that he need not take pills and his kidney wont get rejected before he himself dies in coming ten yrs........... isn't it providing more quality of life?? What r other risks excluding common things to both drugs and aids?

drlouis · Credits: 5374 My Scrapbook

there can not be graded/desired immunosuppression(objective/quantifiable) which can be obtained with kidney obtained from aids pt to pevent acute or chronic rejection...

and imagine a esrd pt (who has received aids organ) with chronic diarrhoea and extensive thrush and all....

U cannot control the immunosuppression with this method.....unlike by giving drugs which can be monitored and adjusted in case pt goes for increased immunosuppression....

just reasoning it out....

ratnakar_potla · Credits: 5703 My Scrapbook My Reading List 2 Books

ok it sounds logical and may be this is what is expected............ my professor put this to me.........may be he needs this controllable aspect

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