Page 1 of 1: MCQ "3"

wasem · Credits: 8632 My Scrapbook

Question 10. Apoptotic cells:

a. Exclude vital dyes
True False

b. Provoke an acute inflammatory reaction
True False

c. May be disposed of by neighbouring cells
True False

d. Contain enzymatically degraded nuclear fragments
True False

e. May be seen in areas of tissue necrosis
True False

Question 11. The following are correctly paired:

a. Gangrene - anaerobic bacteria
True False

b. Karyorrhexis - reversible cell injury
True False

c. Fatty change - alcohol
True False

d. Free radicals - cell membrane damage
True False

e. Venous infarction - testicular torsion
True False

Question 12. The following statements are true:

a. C5a of the complement system causes opsonisation
True False

b. Plasmin can activate complement via the classical pathway
True False

c. Clotting factor XII is also known as the Hageman factor
True False

d. Factor VIII deficiency (haemophilia) leads to defective haemostasis
True False

e. Plasma fibrinogen is insoluble
True False

Question 13. The following statements are correct:

a. Fibrin is a soluble protein
True False

b. Clotting factor VIII requires vitamin K for its synthesis
True False

c. The intrinsic coagulation pathway is triggered by exposed collagen
True False

d. Platelet aggregation is promoted by thromboxane A2
True False

e. Disseminated intravascular coagulation (DIC) results in an increase in the amounts of measurable clotting factors in the plasma
True False

Question 14. The following statements are true:

a. Mural thrombus in the left ventricle may embolise to the brain
True False

b. Thrombosis occurs in veins and arteries
True False

c. Vascular endothelium produces prothrombin
True False

d. Atherosclerosis only occurs in large arteries with turbulent blood flow
True False

e. The pale areas in a thrombus are caused by trapped white blood cells
True False

Question 15. The following statements are correct:

a. Increased levels of high density lipoproteins (HDLs) predispose to atherosclerosis
True False

b. Dietary cholesterol levels are directly related to plasma cholesterol levels
True False

c. Atherosclerotic plaques contain proliferating smooth muscle cells
True False

d. Atherosclerosis is an important cause of aneurysm formation
True False

e. Thrombus commonly develops on atherosclerotic plaques
True False

Question 16. The following are correctly paired:

a. Lines of Zahn in a thrombus - white blood cells
True False

b. Embolus - fragments of thrombus
True False

c. Abdominal aortic aneurysm - leg ischaemia
True False

d. Myocardial infarction - ventricular mural thrombus
True False

e. Cerebral infarction - deep vein thrombosis
True False

Question 17. The following are correctly paired:

a. IgG - cannot cross placenta
True False

b. CD8 - class II MHC
True False

c. IgM - complement activation
True False

d. B cells - cell-mediated immunity
True False

e. Interleukin-1 (IL-1) - fever
True False

Question 18. The following statements are true:

a. Asthma is primarily a T cell-mediated immune disease
True False

b. Skin prick tests are a useful way of predicting immediate hypersensitivity reactions
True False

c. Rheumatic fever is thought to be immune complex-mediated
True False

d. Cyclosporin A (immunosuppressive agent) is nephrotoxic
True False

e. The complement product C3a can cause non-IgE-mediated mast cell degranulation
True False

Question 19. Immune complexes:

a. Are made up of antigen and antibody
True False

b. Contain antibody of the IgG class
True False

c. Are usually insoluble
True False

d. Combine with complement, which initiates an inflammatory reaction
True False

e. Are responsible for post-streptococcal glomerulonephritis
True False

aungnyein · Credits: 530 My Scrapbook

Q.10.(b)False.Apoptotic cells do not provoke an acute inflammatory reaction.
(d)True.Apoptotic cells contains enzymatically degraded nuclear fragments.
(e)True.Apoptotic cells may be WBCs.
Q.11.(a)True.Gangrene may be associated with anaerobic bacteria.
(b)False.Karyorrhexis is not reversible.
(c)True.Fatty change(fatty liver) may be due to alcohol.
(d)True.Free radicals are associated with cell membrane damage.e.g,Red cell membrane.
Q.12.(c)True.Hageman factor is factor XII.
Q.13.(b)False.Vit K dependent clotting factors are II,VII,IX,X.
(c)True.Intrinsic pathway is triggered by exposed collagen.
(d)True.Thromboxane A2 causes vasoconstriction and platelets aggregation.
(e)False.Clotting factors may be scanty in plasma in case of DIC.
Q.14.(e)False.Pale area in thrombus is due to fibrin deposition.
Q.15(a)False.HDL is good cholesterol and it reduces the chance of artherosclerosis.
Q.16(a)False.Line of Zahn in thrombus is due to alternate deposition of fibrin and platelet.
(b)True.Embolus is fragment of thrombus.
(e)True.Cerebral infarction may be due to embolus from deep vein thrombosis.
Q.17(a)False.Ig G is the only Ig which can cross the placenta.
(b)False.CD 8 is associated with class I MHC and CD 4 is associated with class II MHC.
(d)False.B cell is associated with antibody mediated immunity.

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