Page 1 of 1: MCQ "1"

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Question 1. Transferrin is involved in the following (indicate true or false):

(a) Transport of iron.
True False

(b) Utilization of iron.
True False

(c) Hormone metabolism.
True False

(d) Diagnosis of Wilson's disease.
True False

(a) Paraprotein bands usually consist of structurally identical immunoglobulins.
True False

(b) Paraproteins derive from plasma cells resulting from a single B-cell clone.
True False

(c) Paraproteins are exclusively seen with malignant disease.
True False

(d) Bence Jones proteins are seen only in the presence of serum paraproteins.
True False

(e) IgE is the most common paraprotein.
True False

Question 3. Which, if any, of the following compounds are inhibitors of platelet aggregation?

(a) Adenosine diphosphate.
True False

(b) Aspirin.
True False

(c) Thromboxane A2.
True False

(d) Clopidogrel.
True False

(e) Prostacyclin.
True False

Question 4. Which, if any, of the following statements is/are true of classical hemophilia (factor VIII deficiency)?

(a) Autosomal dominant inheritance.
True False

(b) Prolonged prothrombin time.
True False

(c) Prolonged activated partial thromboplastin time.
True False

(d) Aspirin administration is safe.
True False

(e) Prolonged skin bleeding time.
True False

Question 5. Which, if any, of the following statements is/are true of tissue-type plasminogen activator (t-PA)?

(a) Used in treatment of acute myocardial infarction.
True False

(b) Inhibited by α2 antiplasmin.
True False

(c) Synthesized by vascular endothelial cells.
True False

(d) Activity is stimulated by fibrin.
True False

(e) High therapeutic doses can cause excessive bleeding.
True False

Question 6. Which, if any, of the following statements is/are true of antithrombin?

(a) Cofactor for the anticoagulant drug, warfarin.
True False

(b) Inactivates coagulation factor VIII.
True False

(c) Inactivates coagulation factor X.
True False

(d) Congenital deficiency causes excessive bleeding.
True False

(e) Inheritance of deficiency is autosomal dominant.
True False

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