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Quick Scroll dermatologic condition 02.26.06 (2 years ago) #1

what is meant by Scrofuloderma? in whom it is found?
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Quick Scroll 02.26.06 (2 years ago) #2

Scrofuloderma results from breakdown of skin overlying a tuberculous focus, usually at a lymph node but also at the skin over infected bones or joints. Historically, a high prevalence of scrofuloderma was seen in children infected with M bovis from contaminated milk. The oral or tonsillar primary lesion progresses to cervical adenitis, formation of cold abscesses, and secondary breakdown of overlying skin.

Lesions present as firm, painless, subcutaneous nodules that gradually enlarge and suppurate, then form ulcers and sinus tracts in overlying skin. Typical ulcers have undermined edges and a floor of granulation tissue. Typical tubercles with acid-fast bacilli are found in the lower dermis and walls of the ulcer or abscess. Tubercle bacilli usually can be isolated from the purulent discharge. Tuberculin sensitivity usually is marked. Spontaneous healing can occur but often takes years and is accompanied by the formation of hypertrophic scars. Lupus vulgaris may develop in the vicinity of healing scrofuloderma.
Metastatic tuberculous abscess (tuberculous gumma) is a variant of scrofuloderma that occurs following hematogenous spread of mycobacteria to skin in tuberculin-sensitive individuals. Painless, fluctuant, subcutaneous abscesses form singly or at multiple sites, then break down into fistulas and ulcers resembling scrofuloderma. Typically, these lesions occur in malnourished children or in severely immunosuppressed patients.
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Quick Scroll 04.10.06 (2 years ago) #3

thanx
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Quick Scroll 08.23.06 (1 year ago) #4

advice on books to read?
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Quick Scroll 10.19.06 (1 year ago) #5

ya its basically a kind of skin tb which us due to underlying lymphnode involvement...
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