Page 1 of 1: obs

aadit · Credits: 1720 My Scrapbook

35 yr old femaleith choriocarcinoma TOC
D/C
radiotherapy
hystrectomy
chemotherapy

ans given is chemotherapy

Sanya · Credits: 611 My Scrapbook

Ans.D.Chemotherapy

Choriocarcinoma is sensitive to chemotherapy, therefore it is treatment of choice.

In the same time, placenta-site trophoblastic tumour is insensetive to chemotherapy, therefore hysterectomy is recomended .

Staging and Managment of Malignant GTN:

Stage I: disease confined to uterine corpus
Management: single agent chemotherapy if fetility deseired;
1st line: MTX-FA, 90% remission rate,
2nd:ACT-D
combination chemotherapy if resistant
Hysterectomy if placental-site tumour or fertility not desired.

Stage II : metastatic disease to vagina /pelvis
Management: high risk: combination chemotherapy:MXT-FA and ACT-D,
low risk:single agent chemotherapy :start with MTX-FA.

Stage III: metastatic disease to lungs
Management: high risk: combination chemotherapy:MXT-FA and ACT-D,
low risk:single agent chemotherapy :start with MTX-FA.

Stage IV: distant metastic sites including brain,liver, kidney, GI tract.
Management: aggressive combination chemotherapy plus radiation for brain mets.

Toronto Notes, 2004, GY, 50-51.

Sanya

		Sign In New User? Sign Up Sign in to access your control panel and messenger!
				TechZone \| SpiderNevi \| HowTo? \| Scrapbook!