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Biostatistics MCQ Bank Forum Hot - Unasnwered
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Quick Scroll Biostatistics 11.15.05 (2 years ago) #1

which of the following results gives the reader the most info concerning statistical significance,sample size,and strength of association?

a:a relative risk of 2.5 with 95%confidence interval of 2.0 to 3.1
b:a p value of 0.0004 and an alpha of 0.05
c:a relative risk of 5.0 with 95% confidence interval of 0.1 to 9.8
d:a p value of <0.05 and relative risk of 2.5
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Quick Scroll 11.15.05 (2 years ago) #2

I think it should be B, as very small p value gives high value of significance and large sample size. 0.5 alpha gives low false positivity!
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Quick Scroll 11.15.05 (2 years ago) #3

well i thought the same..!
but the answer given is a
a narrow confidence limit does help but how to compare a and b
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Quick Scroll 11.15.05 (2 years ago) #4

Actually b has a shortcoming of strength of association! relative risk is a direct measure of it! low alpha error means good positive predictive value, but then PPV does not give a measure of strength of association! Rest I am not sure!
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Quick Scroll 11.15.05 (2 years ago) #5

thanks! and what about confidence interval
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Quick Scroll 11.17.05 (2 years ago) #6

Well, the only problem I see with (a) is how to say it has large sample size! All I can say is that confidence interval depends on mean and standard error. Standard error itself depends on standard deviation and sample size. If we keep standard deviation constant then large sample size will give small standard error and hence small confidence interval. It very well fits with option (a) provided the assumption of fixed standard deviation holds!
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Quick Scroll 11.17.05 (2 years ago) #7

yeah that makes sense..the q is from bhatia gt..wonder where they picked it up from..thanx neway
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Quick Scroll 11.20.05 (2 years ago) #8

Meta Analysis of Chi Square Study Identifies Insignificant Similarities Among P Values.




Statistician Melvin Beuberhiem explains that “Recent studies refute the finding that the null hypothesis analysis was not improperly under-powered, and assert that the previous result, as an inverse function of one minus the positive predictive value divided by the sensitivity, was significant in an intention to treat cohort, implying a higher number needed to treat. The zaney thing was, the odds ratio remained unchanged.."
He then confessed epidemiology was “a sham,” concocted by Steven Hawking to score with chicks

sorry friends for being too offbeatish in this forum but couldnt help!! icon_lol.gif
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Quick Scroll 10.24.06 (1 year ago) #9

The answer should be a. The advantages of of CI's over the statistical tests is , they give an idea of all probable values for the population parameter and in that respect contain much more information than a single p value. They immediately give an impression of the precision of the estimate. As such they make a qualitative appreciation of ( the lack of) statistical power possible. Very high CIs carry a high risk of beta error...
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Quick Scroll 05.29.07 (1 year ago) #10

ans is a.)
coz..i)R.R= 2.5 is a positive association between the two factors..i..e. the strength of association
ii)C. I. = 95% IS p</=0.05 therefore statistically significant asso.
iii)now main thing is....in a std. normal curve, narrow confidence interval indicates distibution of means in a narrow area..which in turn indicates large sample size..
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