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Quick Scroll Re: patho- 12.04.06 (1 year ago) #21
clrsky wrote:
splenic macrophages in gauchers differ from those in ceroid histiocytes by staining positive for
a lipids
b pospholipids
c aci fast stains
d iron


Gaucher's disease has an autosomal recessive pattern of inheritance. A deficiency of -glucocerebrosidase causes an accumulation of sphingolipid within phagocytic cells throughout the body

Bone marrow aspirates reveal typical Gaucher cells, which have an eccentric nucleus and periodic acid-Schiff (PAS)-positive inclusions,

The production of a recombinant form of the enzyme glucocerebrosidase (imiglucerase) for intravenous administration on a regular basis now permits a reduction in total body stores of glycolipid

All patients with Gaucher disease have nonuniform infiltration of bone marrow by lipid-laden macrophages, termed Gaucher cells.----CMDT & others
iron
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Quick Scroll Pathology -STAINING 05.27.07 (1 year ago) #22
SPLENIC MACROPHAGES IN GAUCHER'S DISEASE DIFFER FROM THAT IN CEROID HISTIOCYTOSIS BY STAINING POSITIVE FOR:
1.LIPID.
2.PHOSPHOLIPID.
3.ACID FAST STAIN.
4.IRON.
I HAVE NO IDEA.
PLEASE HELP.
THANKX.
REGARDS.
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Quick Scroll 05.29.07 (1 year ago) #23
Quote:
decembermist wrote:
ans b)

ceroid hitiocytosis / sea- blue histiocytosis : phospholipids

gaucher's d/s : lipids


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gandalf wrote:
Q is : splenic macrophages in gaucher's disease
differ frm those in ceroid histiocytosis by staining positive fr...

frm ur observation ans shud b a)???


i agree that answer would be a).
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Quick Scroll 05.29.07 (1 year ago) #24
the answer is option 1. lipids
i request all users to use the option "search forums" before posting a question , sometimes they have been discussed already in detail.
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Quick Scroll 06.05.07 (1 year ago) #25
THANKX SMITA.
REGARDS.
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Quick Scroll 06.15.07 (1 year ago) #26
yeah thxz dude
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Quick Scroll 10.29.07 (8 months ago) #27
Yeah Thanx all of u.....!!!!
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