Okazaki fragments is a relatively short fragment of DNA (with an RNA primer at the 5' terminus) created on the lagging strand during DNA replication. -wikipedia and can only form in dsDNA replication.
type b impedance curve,lymph node enlarged in a 45 year old man
1,nasopharyngeal cancer,
2.fluid in middle ear.
3.tumor in int ear,
4.sensorineuronal hearing loss.
is the anser b.pl comment. are options given correct.
dr.jaya
This is the correct Q & options wth A
Q.type b impedance curve,conductive deafness,enlarged cervical lymph node in post.triangle in a old man,whtz the diagnosis?? 1,.nasopharyngeal cancer,
2.middle ear carcinoma
3.Middle ear T.B.
4.sensorineuronal hearing loss.
Nasopharyngeal carcinoma
Sex: A male preponderance exists. The male-to-female ratio is approximately 2:1.
Age:
Nasopharyngeal carcinoma has a bimodal age distribution. A small peak is observed in late childhood, and a second peak occurs in people aged 50-60 years. Childhood nasopharyngeal carcinoma is usually a disease of adolescence.
History: Nasopharyngeal carcinoma rarely comes to medical attention before it has spread to regional lymph nodes. Enlargement and extension of the tumor in the nasopharynx may result in symptoms of nasal obstruction (eg, congestion, nasal discharge, bleeding), changes in hearing (usually associated with blockage of the eustachian tube, but direct extension into the ear is possible), and cranial nerve palsies (usually associated with extension of the tumor into the base of the skull).
One study indicated the following symptoms:
Nasal symptoms, including bleeding, obstruction, and discharge (77.5%)
Ear symptoms, including deafness and tinnitus (73%)
Headaches (61%)
Neck swelling (60%)
Physical:
The most common physical finding is a neck mass, which is observed in 80% of patients. Painless firm lymph node enlargement is present.
Neck involvement is often bilateral; the most common nodes involved are the jugulodigastric and upper and middle jugular nodes in the anterior cervical chain.
Cranial nerve palsy at initial presentation is observed in 25% of patients.
On nasopharyngoscopy, a mass arising in the nasopharynx is often visible. The most frequent site is the fossa of Rosenmüller.
A paraneoplastic osteoarthropathy has been described in patients with widespread or recurrent disease.
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