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Quick Scroll Psychiatry : MANIA 07.21.06 (2 years ago) #1

Treatmant of choice for rapidly cycling mania?
Is it lithium,carbamazepine,or valproate?
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Quick Scroll 07.21.06 (2 years ago) #2

Individuals with the rapid cycling form of bipolar disorder represent 13% to 20% of the bipolar population.
Although lithium remains the treatment of choice for classic bipolar disorder, failure rates as high as 72% to 82% have been reported for lithium among those who have the rapid cycling variant. Treatment alternatives, including the use of divalproex sodium and carbamazepine, have shown promise for this often treatment-refractory group of patients. Predictors of positive outcome for the acute and prophylactic management of mania with divalproex sodium have emerged; they include nonpsychotic mania, the occurrence of decreasing or stable episode frequencies, mild mania, and mixed states. Predictors for positive acute and prophylactic antidepressant responses to divalproex sodium include nonpsychotic mania, increasingly severe mania, and the absence of borderline personality.Mixed results have been reported for studies using carbamazepine therapy for the treatment of rapid cycling bipolar disorder.Some investigators have reported success with carbamazepine in conjunction with other medications, while others have not.

From this i conlude that Although both sodium valproate and carbamazepine can be used for treatment of rapid cycling mania.....sodium valproate is better to carbamazepine.
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Quick Scroll 07.21.06 (2 years ago) #3

refer to
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Quick Scroll 07.21.06 (2 years ago) #4

Also read this:

Lamotrigine has had been successful in controlling rapid cycling and mixed bipolar states in people who have not received adequate relief from lithium, carbamazepine and/or valproate
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Quick Scroll 07.21.06 (2 years ago) #5

valproate
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Quick Scroll 07.22.06 (2 years ago) #6

please check this thread ,question already discussed in detail:
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Quick Scroll 10.19.07 (1 year ago) #7

valporate
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Quick Scroll 01.27.08 (10 months ago) #8

valproate
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Quick Scroll Help please 01.28.08 (10 months ago) #9

1)A lady aged 61yrs years who was depressed and to doctors questions was answering "i dont know"
2)A person who is being asked for his age and he replied 80, but after that whatever question was asked about his life, etc. he replied same 80.
3) A women who had history of low mood ,sleep disturbance and presented this time with agitation and irritibilaty

Please answers with explanation.

a. dspression with psychotic symptoms
b. shizo effective
c. major depression
d. pseudo dementia
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Quick Scroll 04.27.08 (7 months ago) #10

1)A lady aged 61yrs years who was depressed and to doctors questions was answering "i dont know"
2)A person who is being asked for his age and he replied 80, but after that whatever question was asked about his life, etc. he replied same 80.
3) A women who had history of low mood ,sleep disturbance and presented this time with agitation and irritibilaty

Please answers with explanation.

a. dspression with psychotic symptoms
b. shizo effective
c. major depression
d. pseudo dementia
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