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NIMHANS
-MD/DPM-07...recalled q. by nadu....
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05.15.08 (3 months ago)
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NIMHANS
-MD/DPM-07
total=160 q
time=2hrs
negative=0.5 marks
marking with NB-pencil
1-Gradenigo’s synd true a/e
a-Persistent ear discharge
b-Facial Palsy
c-Deep seated retrorbital pain
d-Lat. rectal palsy
2-Mittelschize is
a-Ovular pain
b-Ovarian dysmenorrhoea
c-Membranes dysmenorrhoea
3-Seligmans disease is
a- heavy chain disease
b- heav chain disease(Franklins)
4-Klaskins tumor is at
a-Bile duet
b-Pancreas
c-Small intestine
d-Large intestine
5-% of Schizophrenia in monozygotic twins
a-40-50%
b-10-20%
6-Champene bottle app. Of legs
a-Deep venous incompetetance
b-DVT
7-Christmus tree cataract seen in
a-Diabetes
b-Myotonic Dystrophy
8-True about Leber’s optic atrophy a/e
a-Pain
b-Central visual loss
c-Mitochondrail mut.
d-Optic atrophy
9-MC cause of UGI bleeding
a-Peptic Ulcer
b-Esophageal varices
10-MC site of Ca-Pancreas
a-Head
b-Tail
c-Body
11-MC cause of intestinal obstruction in neonate
a-Volvulus
b-Meonium ileus
c-Hirschprug’s
12-2 SD means
a-95%
b-97%
c-65%
13-Def. Of Agarophobia
a-Fear of open space
b-Fear of close space
14-Chi-square test is for
a-Association
b-Correlation
c-Variance
d-Regression
15-Public restroom uncomfortable is
a-Social Phobia
b-Clustrophobia
c-Anxiety neurosis
d-Agarophobia
16-Psychogenic Seizures true a/e
a- prolactin
b-Sec. To underlying psych. Disorder
17-MND is seen in all foll. Popular personalities expect
a-Stephan Hawkins
b-Md. Ali
c-Gehrig
d-Zoe Ladon
18-Fibre passing through post limb of int. capsule
a-Corticopetal
b-Corticofugal
c-Corticonuclear
19-Isaac’s synd
a-Myotonia
b-Neuromyotonia
20-TRH released from
a-Pre-Optic
b-Suproventricular nuleus
c-Median eminance
d-Arcuate nucleus
21-All of foll. Released/ secreated from both Brain &endocrine gland except
a-Dopamine
b-Oxytocin
c-Cortisone
d-Somatostatin
22-Term “Schizophrenia” coined by
a-Bluer
23-True is
a-Neural crest l/t sp.cord.
b -Limb buds are derived from lateral axial mesoderm
c-Embryo means first 10 wks of gest.
24-Noble Prize won by
a-Kreplin
b-Frend
c-Egas Moniz
25-MC symp. of multiple myeloma
a-Bone pain
26-Mental health Act passed in Loksabha
a-1985
b-1986
c-1987
d-1989
27-Peristent increase in synaptic Tranmission is d/t
a-Long term sensitization
b-Long term Potentiation
c-Short term Sensitization
28-Cocain Poisoning manifests as:
a-Anticholinergic
b-Antiadrenergic
c-Antiserotonergic
d-all
29-True about M.Gravis:(H16-173-174)
a-Poor pupillary response
b-Difficulty in opening eye
c-Difficulty in closing eye
d-Diplopia
30-true a/e
a-M.Gravis-Ab to nicotinic muscarinic receptor
b-M.Sclerosis-Ab to Myelin
c-Hashimoto’s-Ab to TSH
d-Grave’s-Ab with stimulated TSH receptor
31-Influenza belongs to which group of viruses
a-Orthomyxo
32-HIV true a/e
a-Opp. Infection at less than 200
b-DIVA virus associated with HIV l/t increase syndromic features
c-Ab to GAG gene persists through out disease
d-Ab to envelop gene persists throughout disease
33-True is a/e
a-Karryoxix is reversible
b-Free radicals l/t cell membrane damage
34-Head engagement in primi occurs
a-32-36wk
b-36-38wk
c-28-32wk
d-38-42wk
35-Dangerous Placenta Previa:
a-Type II post
b-Type II ant
36-D/D of Hypopigmentation a/e
a-Freckles
b-T.versicolor
c-Leprosy
d-T.alba
37-Vesicobullous lesion a/e
a-Lichen Planus
b-Derm. Herpetifurmis
c-T.fluens
38-Luc’s Abscens
a-Over the mastoid
b-Behind the mastoid
c-Underlying the antrum
d-Tegmen Tympanum
39-True is
a-ECT discovered by Cerlet & Binniti
40-ECT is effective in with type of Schizophrenic
a-Paranoid
b-Catatonic
c-Hebephrenic
41-True about ECT
a-Modified preferred over unmodified
42-D/D of Catatonia a/e
a-Wernicke’s encephalopathy
b-CNS neoplasms
c-Hepatic encephalopathy
43-MC Aphasia is metab encephalophathy
a-Anomic Aphasia
44-Which of the following are a neurotransmitter a/e
a-Glycine
b-GABA
c-Glutamate
d-Ach.
45-Amyloid stained by
a-Congo-red & sulfated alcaine blue
b-Congo-red & sudan-black
c-Sulfated Alcaine blue & sudan black
46-Which of the following Prt. Sub. Has antigenic potential to Insulin
a-10000
b-20000
c-30000
d-1 lakh
47-All are Br. Of Rt. Coronary A a/e
a-Conus
b-Acute marginal
c-Obstuse marginal
d-AV nodal
48-Which of the following is metabotrophic receptor
a-NMDA
b-GABA
c-5 HT
d-Glutamate
49-Prion disease true a/e
a-MC variant is spuradic CJ
b-CJ ds is d/t exposure to beef
c-Kuru is d/t Cannabism
d-Scrapie is a/k/a Spongioform encephalpathy
50-All are spirochaetal ds. Except:
a-Tick typhus
b-Lyme’s ds
c-Relapsing fever
51-H.simplex I manifests as:
a-Gingiostomatitis
b-Cut. Manifestation
c-Genitourinary infection
52-Early manifestation of Enteric fever except:
a-Epistaxi
b-Rose spots
c-GI hemarrhage
d-Hepatosplenomegally
53-Asbestosis true a/e:
a-Mesothelioma
b-Bronchogenic Ca
c-Bronchictasis
d-Interstitial fibrosis
54-Extrapul TB MC manifestation is
a-Skeletal TB
b-Genitourinary TB
55-True about Skeletal muscle a/e:
a-Striated
b-Long T tubules
c-Have Troponin system
d-No synctium
56-In preg all the following changes l/t drug diposition except:
a-increase ECF volume
b-increase Albumin
c-decrease DI motility
d-Renal blood flow
57-Safer Anti HIV in preg
a-Reserpin
b-Diuretics
c-Atenolol
d-Propranolo
58-Antidependent not eseful is CVS disease pt is
a-Sertulin
b-Citalapram
c-Amitryptilin
d-Citalapram
59-Rantae is how many times potent than cimetidine:
a-2 times
b-3 times
c-4 times
d-5 times
60-Darkly pigmented liver seen in:
a-Dubin-Johnson
b-Rotor
61-Classical indication of neurosurgical intervention is
a-Rx refractory OCD
b-Rapid Cyders not resp to Rx
c-Chr. Schizophrenia
62-Absolute C/I of OCP a/e:
a-Porphyria
b-GB disease
c-Cerebrovascular disease
d-Hepatic disease
63-Which of the following is absolutly C/I in Hepatic disease:
a-INH
b-Rifabutin
c-Ethambutol
d-Streptomycin
64-Ceftriaxone true a/e:
a-CSF penetration good
b-excreted in bile
c-excreated in urine
d-short acting
65-Immune resp. in CNS is mediated by
a-Astrocytes
b-Microglia
c-Oligodenrites
d-Schwann cells
66-Night soil & refuse disposal are disposed by:
a-Composting
b-Dumping
c-Controlled Tipping
67-Conn. Of Hippocampus to Thalamus by
a-Amman’s horn
b-Mamillothola
c-Hypothalamus
68-Which of the following pathway not relay directly to cortex:
a-Auditory
b-Visual
c-Olfactory
69-Rx of major Depression a/e:
a-Cognitive therapy
b-Interpersona; psychotherapy
c-Antidepresasant
d-Mood stabilizer
70-Har chandes in post menopausal a/e:
a-increase LH & FSH
b-decrease LH & FSH
c-decrease estrogen
d-increase progestron
71-Hematocrit means
a-41% of Hb in plasma
b-41% of RBC WBC platelet
c-41% of only erythoid precursor
72-All are steroid except:
a-16--hydroxylare
b-Relaxin
c-Estrone
d-Pregnelone
73-Lateral Medullary synd. True is
a-Ispilat thickening & paralysis of Tongue
b-Ipsi pain numbness
c-Contralat. Paralysis of limb
d-Bilat. Tract involvement
74-All true about pressure Hydrocephalus except:
a-Dementia
b-Urinary incontinence
c-Gait apraxia
d-Aphasia
75-True about Pseudotumor cerebri:
a-increase CSF pressure
76-Reversible cause of Dementia:
a-Huntington’s
b-Alzhiemer’s
c-Pressure hydrocephalus
d-Metab. Encephalopathy
77-Which of the following is true a/e:
a-Inverse agenist acts opposite to agenist
b-Antagenist has no intrinsic action
c-Antagenist doesn’t block inverse agenist
d-Antagenist block agenist
78-MC cause of chronic back pain
a-Spondylosis
b-Ank. Spondylitis
c-Lumbar disk disease
d-Sp. Cord stenosis
79-Unilat stepping gaint D/D a/e:
a-L5 neuropathy
b-Sciatic neuropathy
c-Peroneal neuropathy
d-distal neuropathy
80-Edema d/t cardiac cause true a/e:ss
a-increase uric acid
b-increase liver enzyme
c-decrease sr. Na
d-increase sr.creat:sr. urea ratio
81.All the following are CDC cat-A micro-organism of biological terrorism except:
a.Anthrax
b.Clostridium
c.Alphavirus
d.Flavivirus
82.Meningococci are:
a.Gm+ve cocci in chain
b.Gm+ve cocci in pair
c.Gm_ve diplococci
d.Gm_ve rods
83.MRSA true is:
a.also resistant to qiunolones
b.not resistant to cephalosporins
c.vanco is DOC
d.50% of hospital Staph.auereus are MRSA
84.True about leukoplakia all except:
a.unless proved otherwise is precancerous
b.50% malignant risk
c.occurance on ventral surface of tongue
d.carries more risk of malignancy
85.True about renal cell carcinoma:
a.a/w von-hippel lindau
b.adenomatous differentiaon common
c.smoking is a risk factor
d.hematogenous spread is rare
86.POLYDACTYLY is seen in :
a.prader-villi syndrome
b.carpenter syndrome
c.cohen’s syndrome
d.alosrom’s-holm’s syndrome
87.Chemosis is inflammation of:
a.cornea
b.conjunctiva
c.sclera
d.
88.MC siezers in late infancy & early childhood:
a.Absence
b.Febrile
c.gen.tonic clonic
d.none
89.True about cluster headach is a/e:
a.MC in male
b.unilateral
c.nocturnal
d.throbbing in nature
90.Used in treatment of cluster headach:
a.propranolol
b.lithium
c.analgesic
d.
91.Theurapetic dose of digoxin is a/w ECG changes of:
a.QT shortening
b.short pr interval
c.Increase T wave
d.
92.Which of following drug has least favourable theurapetic index:
a.diazepam
b.lithium
c.
d.
93.Prophylatic level of lithium in bipolar disorder:
a.0.2-0.5
b.0.5-1.2
c.1.2-1.5
d.
94.Use of ECT in bipolar disorder :
a.treat both depression & mania
.treat only depression
c.treat only mania
d.niether depression nor mania
95.ALPHA-SYNUCLEIN is high in :
a.senile plaques
b.lewy bodies
c.neurofib.tangles
d.all
96.True about alzhiemer’s a/e:
a.senile plaques
b.amyloid angiopathy
c.neurofibrillary tangles
d.hirano bodies
97.Adverse effects of fluoxetine are a/e:
a.gittriness
b.headache
c.hypertension
d.sex.dysfunction
[snip].Least wt gain is seen with:
a.lithium
b.topiramate
c.valporate
d.olanzepine
99.Drug used in nicotine addiction:
a.bupropion
b.buspirone
100.Initial investigation of acute stroke:
a.CT scan with contrast
b.CT scan without contrast
c.CT angiography
d.MRI
101.All are cytokines except:
a.interferon
b.IL-3
c.TNF
d.Anti-rh-globulin
102.True about panik attack:
a.occurs in special circumstances
b.stress induced
c.fear of impending doom with physical symptoms
d.
103.True about radiological features of schizophrenia a/e:
a.atrophy of gyri
b.enlargement of ventricles
c.high volume of pareital lobe
d.
104.True about depression a/e:
a.cortical hypersecretion
b.non-suppression of cortisol to dexamethasone adminstration
d.Blunted tsh response to TRH
d.adrenal atropy
105.Glasgocoma scale includes a/e:
a.motor
b.verbal
c.eye-opening
d.
106.Maximum score in MINI MENTAL STATUS is:
a.23
b.28
c.30
d.40
107.Which of following is incorrect:
a.testicular tortion=venous infarction
b.gangrene=anaerobic bacteria
108.Which of following is negative symptoms of schizophrenia:
a.hallucination& delusion
b.decreased emotional expression & anhedonia
c.
d.
109.MC type of hallucination in schizophrenia:
a.auditory
b.visual
c.both
d.none
110. Predictivity of bipolar disorder occurring in a depressed person depends on:
a.family history
b.a/w psychotic features
c.
d.
111.In elderly person depressive symptoms a/w cognitive deficit are known as:
a.dementia
b.dementia precox
c.pseudodementia
d.
112.MC breast carcinoma:
a.medullary
b.ductal
c.lobular
d.comedo
113.Pre-occupation with physical defect is:
a.hypochondriasis
b.somatisation
c.
d.
114.All causes depression except:
a.ibuprofen
b.propranolo
c.cortisone
d.
115.Dehydrated pt, treatment is :
a.0.9% NaCL
b.5% glucose
c.10% glucose
d.
116.True about h-simplex encephalitis:
a.cowdry intranuclear bodies
b.intranuclear necrosis
c.cytomegalic inclusion
d.
117.Not characteristic of schizophrenia:
a.illusion
b.hallucination
c.delusion
d.disorganisedbahavior
118.MC external abdominal hernia:
a.inguinal
b.emoral
c.umbilical
d.incisional
119.In NARCOLEPSY true a/e:
a.REM latency decreased
b.density of REM is increased in first few hrs of sleep
c.predominant stageII sleep
d.
120.Man at rest with eyes open frequency of waves on EEG:
a.>30
b.13-30
c.8-13
d.<8
121.upper esophagus is supplied by:
a.inf.thyroid artery
b.sup. thyroid artery
c.esophageal br.of aorta
d.bronchial artery
122.Essential a.a a/e:
a.argenine
b.alanine
c.leucine
d.isoleucine
123.True a/e:
a.Niacin is not a stict vitamine
b.Vit B12 is measured by aminotransferase
c.Pancreatic insufficincy causes B12 deficincy
d.Homocysteine deficincy is a/w atherosclerosis
124.Highest PH is :
a.pancreas
b.intestinal
c.gastric
d.saliva
125.True a/e:
a.fibrin is soluable
b.factor 8 is vit-K dependent
c.
d.
126.All are disruptive developmental disorder except:
a.ADHD
b.prepubertal mania
c.oppositinal deficit disorder
d.conduct disorder
127.PATHOLOGICAL INTOXICATION IS:
a.large dose of alcohol
b.low dose of alcohol
c.alcohol with diazepam
d.
128.Specific phosphokinase for inositol second messenger :
a.Phosphokinase A
b.Phosphokinase B
c.phosphokinase C
d.calmodulin
129.100% association in NARCOLEPSY:
a.hypnogogic hallucination
b.cataplexy
c.sleep attacks
d.sleep paralysis
130.True a/e:
a.western blot for DNA analysis
b.
c.
d.
131.Clone is a :
a.Molecules(DNA,RNA,PRT) derived from two separate species
b.molecules derived from single parent
c.a sequence of bacteriophage lambda
d.
132.In hypothyroidism which of following is increased:
a.iodine
b.rT3
c.thyroglobulin
d.
133.Erythropoitin:
a.inhibits proliferation of red cell precursors in bone marrow
b.inhibits proliferation of Hb in marrow
c.stimulates maturation of erythroblast
d.
134.True about paroxysmal nocturnal dypnea except:
a.a/k/a cardiac asthma
b.pt awakens in night with mild pulmonary congestion
c.wheezing seen
d.it shud be differentiated from bronchitis
135.Permenant teeth in single jaw of adult:
a.4incisor,2 canine,4premolar,6 molar
b.2incisor,4canine,4premolar,6molar
c.
d.
136.True about metastasis to bone a/e:
a.majority comes from prostate,lung,breast
b.may be osteoblastic
c.may be osteolytic
d.
137.Treatment of enuresis a/e:
a.vasopressin
b.conditional devices
c.imipramine
d.
138.lesion in prefrontal cortex produces:
a.anasognosia
b.personality changes
c.urinary incontinance
d.
139LENTICULAR nucleus consists of:
a.putamen+globus pallidum
b.putamen+striatum
c.
d.
140.A single episode of depression shud be treated for:
a.4-6 wks
b.6-9 months
c.2 yrs
d.5 yrs
141.Treatment of tardive dyskinesia a/e:
a.transient incresed dose of antipsychotic
b.propranolol
c.benzhexol
d.
142.Major depression is differentiated from depression a/w medical illness by:
a.guilt feeling
b.lack of energy
c.lack of sexual drive
d.insomnia
143.MC type of intracranial hemorrhage:
a.subarachnoid
b.intraparenchiamal
c.subdural
d.
144.According to ICD-10 defenation of borderline paersonality disorder is:
a.impulsivity & instability
b.factitious disorder
c.conversion disorder
d.
145.Bipolar disorder true is a/e:
a.prevalence in male & female is equal
b.doesn’t occur in children
c.
d.
146.Following are harmful to human except:
a.paris green
b.sodium flouride
c.DDT
d.
147.All the following have mean concentration maximum in ICF tha ECF except:
a.K
b.Mg
c.protein
d.Hco3
148.True about wernick’s aphasia:
a.comprehention is impaired
b.repition is impaired
c.d.
149.Glucose is maximamally absorbed in:
a.PCT
b.DCT
c.Collecting tubule
d.Thin loop of henle
150.Which of following is an endogenous peptide:
a.B-endorphin
b.
c.
d.
151.True about lewy body disease a/e:
a.parkison symptoms
b.senile plaques seen
c.
d.
152.True about SEROTONIN SYNDROME:
a. d/t serotonin receptor antagonist
b. b.d/t serptonin receptor agonist
c. c.d/t serotonin agonist & antidepressant
d. d.
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