Page 1 of 1: MEDICINE-GENETICS

jayanta · Credits: 35493 My Scrapbook My Reading List 45 Books

ALL CAN BE USED FOR DNA ANALYSIS EXCEPT:
1.MONOCYTE.
2.LYMPHOCYTE.
3.FIBROBLAST.
4.AMNION CELL.
ANSWER GIVEN IS 3.
BUT I THINK ITS 2.
PLEASE HELP.
REGARDS.

memymyselfin · Credits: 4075 My Scrapbook

drjanak · Credits: 3151 My Scrapbook

Harrisons 17th ed Chapter 64 – Methodologic Approaches to Genetic Testing
DNA testing is most commonly performed by DNA sequence analysis for mutations, although genotype can also be deduced through the study of RNA or protein (e.g., apoprotein E, hemoglobin, immunohistochemistry). The determination of DNA sequence alterations relies heavily on the use of polymerase chain reaction (PCR), which allows rapid amplification and analysis of the gene of interest. In addition, PCR enables genetic testing on minimal amounts of DNA extracted from a wide range of tissue sources including leukocytes, fibroblasts, epithelial cells in saliva or hair, and archival tissues

Robbins – Basic Pathology Section 7 – Genetic & Paediatric Diseases – Diagnosis of Genetic Disease
Fluorescence in Situ HybridizationFISH utilizes DNA probes that recognize sequences specific to chromosomal regions. The ability of FISH to circumvent the need for dividing cells is invaluable when a rapid diagnosis is warranted (e.g., in a critically ill infant suspected of having an underlying genetic disorder). Such analysis can be performed on prenatal samples (e.g., cells obtained by amniocentesis, chorionic villus biopsy, or umbilical cord blood), peripheral blood lymphocytes, and even archival tissue sectionsAnswer: Should be Monocytes

jayanta · Credits: 35493 My Scrapbook My Reading List 45 Books

THANKX ALOT FOR UR REFERRENCE.
REGARDS.

jayanta · Credits: 35493 My Scrapbook My Reading List 45 Books

THANK YOU JANAK.
REGARDS.

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