Page 1 of 1: pathology - anaemia

dynamic · Credits: 637 Preparing for: AIIMS My Scrapbook

hi this is dr ashish nick name dynamic today only i opened an account at dis mail site well its a great boon to med students who r preparing for the entrance i have a question can any one of u ans it
what happens to tibc and % saturation of transferrin in case of iron def. anaemai and anaemia due to chronic disease?

rick12 · Credits: 2812 Preparing for: Maharashtra PG My Scrapbook

in Iron def. anemia TIBC increases and transferrin decreases
in anemia due to chronic disease the TIBC remains normal but transferrin increases (as transferrin is raised in inflammation)
correct me if I m wrong

draashna · Credits: 907 Preparing for: USMLE Step 1 My Scrapbook

Some imp differences between IRON DEF ANEMIA and ANEMIA OF CHRONIC Ds.
Fe def chronic ds
1. SERUM IRON DEC DEC
2 TIBC INC DEC
3.% SATURATION(of transferrin)DEC DEC
4 FERRITIN DEC INC
5 RDW INC NORMAL
6 MCHC DEC DEC
7.FREE RBS PRTOPORPHRIN INC INC
8 TRANSFERRIN REC ACTIVITY INC NORMAL.

Hope that helped..
GL!!

draashna · Credits: 907 Preparing for: USMLE Step 1 My Scrapbook

I had given the spaces n arranged them in tabular form. but guess something went wrong. hope u can understand it like this...
GL!!

aungnyein · Credits: 581 Preparing for: MRCPath Part 1 My Scrapbook

In case of IDA,TIBC must be increased and % saturation of transferrin must be decreased.
In case of anaemia of chronic diseases, both may be normal.

Mystic_mind · Credits: 1624 My Scrapbook

in anaemia of chronic disease, bone marrow aspirate will show increased iron stores when pearls staining is done on it.

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