Friends, so these are some answered and unanswered MCQs.
What is the major antibody of internal secretions (blood, CSF , lymph)? IgG (external secretions ─ IgA)
What is the valence of an immunoglobulin molecule equal to? 2 for G,E,A,D AND theoreticaly 10 for IG M but it can maximally attach to 5 due to stearic hinderence.
What immunoglobulin is a marker for mature B cells and is the antigen receptor of B cells? Fc portion of IgG
What is the only Ig that cannot bind to Staphylococcus protein A? IgD
By which process do antibodies make microorganisms more easily ingested via phagocytosis? Opsonisation
Which immunoglobulin is found as a pentamer and activates complement? IgM
What is synthesized by epithelial cells, protects IgA from degradation, and transports IgA across epithelial barriers? Polymeric Ig receptor
Which Ig cannot activate complement? Ig E does not activate. (Ig A and D activate altenate pathway and Ig G and M the classical)
What cell surface marker is used to distinguish different stages in the maturation of T cells? tdT?
What form of graft involves tissue or organ transplantation between genetically identical twins? Isograft (Syngenic)
What virus is associated with intranuclear inclusions known as “owl’s eyes” inclusions? CMV
What virus is associated with Negri bodies? Rabies
What virus is associated with Guarneiri bodies? Varicella or smallpox?
What virus causes small, pink, benign wart-like tumors and is associated with HIV-positive patients?
What virus is associated with erythema infectiosum or fifth disease? Parvovirus B19
What is the only dsDNA virus?
What are the three non-eveloped RNA virus?
Reovirus
What viruses are associated with Cowdry type A intranuclear inclusions?
What virus is associated with the Norwalk agent?
What virus affects the motor neurons in the anterior horn? Polio
What is the most common cause of diarrhea in children? Rotavirus
What is the most common cause of diarrhea in infants?
With what virus are Downey type II cells associated?
What are the four segmented RNA virus?
Koilocytic cells on a Papanicolau (Pap) smear are indicative of what virus? HPV?
What bacteria constitute the most common cause of nosocomial infections in burn patients and in patients with cystic fibrosis? Pseudomonas
What organism is associated with pneumonia acquired from air conditioners? Legionella pneumophila
What species of bacteria is associated with whooping cough? Bordatella pertussis
What two bacteria are associated with drinking unpasterurized milk? M.bovis, Brucella, Proteus etc.
What organism is associated with gastritis and ulcers? H.pylori
What species of bacteria is associated with traveler’s diarrhea? ETEC
With which organism is “current jelly” sputum associated? Klebsiella
What is the most common cause of enterocolitis?
What organism is so infective that it takes only 1 to 10 organisms to cause an infection? Salmonella typhi
What organism stains bipolar and causes buboes? Yersinia pestis
Rice water stools are indicative of what organism? Vibrio cholerae
With what organism are intracellular gram-negative inclusions in neutrophils associated? Neisseria gonorrhoae
What organism is most likely to cause an infection if you are bitten by a dog or a cat?
What organism needs factor x and NAD in order to grow on growth medium?
What organism is associated with rigid belly and rose spots on the belly? Salmonella typhi
What organism will cause an infection if undercooked or raw seafood is eaten?
What organism is likely to infect you if you get cut the a shell at the beach?
What infective bacteria are found in undercooked hamburgers? Staphylococcus? Or Bacillus cereus?
What organism is said to have a “spaghetti and meatball” arrangement under a microscope? Mallasezia furfur
What fungus is associated with rose gardener’s disease? Sporothrix schenki
What fungus is seen as colored cauliflower lesions?
What fungus is found in soil with bird or bat feces?
Which organism causes San Joaguin fever?
What species of bacteria is responsible for causing endocarditis in IV drug users? Coagulase negative Staphylococci
What fungus causes endocarditis in IV drug users?
What fungus is found in pigeon droppings? Cryptococcus neoformans
What fungus is seen as a yeast with broad-based buds and a double refractile cell wall?
What fungus is stained positive with india ink? Cryptococcus
What virus is the most common causative agent of the common cold in the summer and the fall?
What virus is the most common cause of the common cold in the winter and early spring?
To what family of viruses do dengue, St.Louis, and yellow fever belong? Flaviviridae
What is the name of the [bleep]-shaped virus? Rabies
What virus is responsible for causing the croup and also the common cold in the young and the old?
What is the causitive agent or orchitis, parotitis, and pancreatitis? Mumps
What virus causes hoof-and-mouth disease?
What is the most common cause of bacterial pneumonia?
What is the most common cause of viral pneumonia?
What is the most common cause of pneumonia in children 1 year old or younger?
What is the most common cause of pneumonia in persons with underlying health problems?
What is the most common cause of pneumonia in young children?
What yeast is urease positive? Cryptococcus neoformans
What fungus is a facultative intracellular parasite of the recticular endothelial system?
What virus is helical and has HN and F glycoprotein spikes?
What virus causes eipdemic keratoconjunctivities?
What is the most common cold virus?
What two viruses have neuraminidase activity? Influenza & Parainfluenza
What is the reservoir for the togavirus?
What two viruses cause pancreatitis?
With what two viruses are Reye’s syndrome associated?
What is the most common cause of bronchiolitis in children?
What is the most common cause of urinary tract infections?
Which three organisms cause heterophilic negative mononucleosis?
What two genera are spore formers?
What bacteria are responsible for woolsorters’ disease? Bacillus anthrax
What bacteria cause subacute endocarditis and dental caries?
Which two organisms can cause sulfur granules in the pus? Actinomyces israelii & Nocardia
What bacteria are responsible for food poisoning from rice, fried rice, and reheated foods? Bacillus cereus
Which bacteria present as a common cause of meningitis in renal transplant patients? Legionella?
What bacteria get inoculated into the body by a puncture wound in the SKIN and also inhibit glycine and GABA?
What bacteria are found in poorly preserved canned food and cause flaccid paralysis?
What bacteria cause myonecrosis?
What bacteria cause pseudomembranous colitis? Clostridium difficile
What bacteria are associated with food poisoning from ham, potato salad, and custards? Staphylococcus
What three bacteria are quellung reactive test positive? Pneumococcus &?
Which organism causes a painful chancre?
What is the predominant anaerobe in the colon?
Which organism causes trench mouth?
Which organism causes Lyme disease? Loa Loa
Which organism causes Weil’s disease? Leptospira
What organism causes Q fever? Coxiella burnetti
Which agent causes pneumonia an college students and military recruits?
What is the tetrad of Jarisch-Herxheimer reaction?
Which spirochete causes Rocky Mountain spotted fever? Rickettsia rickettsii
Which organism causes trench fever? Rochalemia quintana
Which organism causes epidemic typhus? Rickettsia prowazekii
Which organism causes pneumonia in bird owners?
Which organism causes multiple infections by antigen switching? Neisseria gonorrhoea?
Which organism has protein A for an anti-opsonization defense?
Which organism releases endotoxins PRIOR to cell death?
What is the only ssDNA virus? Parvovirus
What is the only DNA virus to replicate in the cytoplasm? Pox virus
What are the three naked DNA viruses?
What is the only DNA virus that has the reverse transcriptase enzyme? Hepatitis B
Which hepatitis virus is an RNA viroid-like virus that needs hepatitis B to be infective? Hepatitis D
Which hepatitis virus is an enveloped RNA flavivirus, which is known for postinfusional hepatitis? Hepatitis C
What antigen is needed to diagnose an infections patient with hepatitis B? HbeAg?
Which type of hepatitis can cause hepatocellular carcinoma? Hepatitis B & C
Which type of hepatitis is a calicivirus? Hepatitis E
Which type of hepatitis is a picornavirus? Hepatitis A
What two antigens need to be positive for a patient to have chronic active hepatitis? HbsAg & HbeAg
In the window phase of a hepatitis B infection, which antibodies do you see? Anti HbC
Which virus is found in the urine of rodents? Hantavirus
Which virus is associated with hairy T cell leukemia?
What are the components of the rubella triad? Heart defect, cataract, deafness
What does Candida albicans do that distinguishes it from other fungi?
Which organism, transmitted by sexual contact, is almost diagnotic by the foul-smelling, green discharge from the vagina and its assocaited itch? Trichomonas vaginalis
Which organism is associated with a diffuse bilateral interstitial pneumonia and with HIV-Positive patients with CD4 counts of or lower? Pneumocystis carinii
What three organs can be affected by Trypanosoma cruzi? Oesophagus, ?
What organism causes kala-azar, which is associated with hyperpigmentation of the SKIN , enlargement of the spleen , and decreased bone marrow activity? Leishmania donovani
Which type of malaria is associated with dark urine? Plasmodium falciparum
What people are “protected” from malaria? Blacks
What type of Plasmodium is banana or crescent shaped when stained with Giemsa stain?
What is the only Plasmodium that is quartan? Plasmodium malariae
What type of Plasmodium produce latent hypnozoites in the liver , which can cause a relapse? Vivax?
What organism is associated with liver abscess, teardrop ulcers, and perforated diapharagms?
What three carcinomas are associated with EBV? Nasopharyngeal CA, Burkitt’s lymphoma, Lymphoma in immunodefient
What is the direction of the strand if a virus has infections +RNA?
What two viruses do not get their envelope from budding but actually from coding?
What glycoprotein in the HIV virus is used for fusion?
What glycoprotein in the HIV virus attaches to CD4?
What protein of the HIV virus is used to detect if a patient is HIV-positve by ELISA?
What two viruses cause progressive multifocal encephalitis?
With what virus do you see Koplik’s spots and Warthin-Finkeldy cells, and possibly subacute sclerosing panecephalitis? Measles
What are known as jumping genes? Transposons
What is the most common viral cuase of myocarditis? Coxsackie B
What virus is associated with heterophil-positive mononucleosis?
What is the only virus to be eradicated? Small pox
What virus, which creates painful vesicular lesion, is a cause of aseptic meningitis? Herpes simplex
What virus attaches to fibroblastic growth factor?
What is the most prevalent viral infection in the USA?
What is the only herpes virus to cross the placenta?
What cells of hepatitis has the highest mortality rate among pregnant women?
What type of hepatitis has the highest mortality rate among present women? HEV
What does hepatitis D virus need from hepatitis B virus to be infective?
What are two hepatitis viruses that can be chronic and can lead eventually of hepatocellular carcinoma? Hepatitis B &C
What are the only two viruses where naked dsDNA is NOT infectious?
What is the only diploid virus?
What type(s) of immune response is the body capable of making when presented with a live vaccine?
What HPV is the causative agent of anogenital warts? condyloma acumintata 6 11 30 42-45 51 54 55 70
What type(s) of immune response is the body capable of making when presented with a killed vaccine?
Who are the “typical” women who present with endometrial carcinoma?
What type of vaccine is the MMR vaccine?
With what virus is postauricular lymphadenopathy associated? Rubella
In what trimester is the fetus most vulnerable to congenital rubella syndrome? 1st
What is the order of the antibodies, from first to last, in an infected patient with hepatitis?
What is the first antigen seen in an individual with hepatitis? HbsAg
What antibody is an indication of low transmissiblity for hepatitis? Anti Hbe
What antibody is an indication of recurrent disease for hepatitis?
Antibodies to what hepatitis B antigen provide immunity? HbsAg
What are three C’s of measles? Cough, Coryza, Conjunctivitis
What are the only two picornaviruses that do NOT lead to aseptic meningitis?
Are antibiotics helpful in treating a disease caused by a prion? No
What is the only part of the virus that is “detectable” during the eclipse period of the viral growth cycle?
What is the only virus to carry its own ribosomes?
What is the term for the period from the onset of an infection to the appearance of the virus extracellularly?
What is the leading cause of diarrhea in the USA?
What organism would cause a patient to present with constant diarrhea after drinking mountain stream water on a camping trip?
What parasite can cause vitamin B12 deficiencies? D.latum (fish tape worm)
What viral infection is associated with black vomit? Yellow fever (American Plague)
What are the two nonspecific chemical defense of the body? tears lysozyme..... acid in stomach,salt FA in sweat
What are the two nonspecific physical defenses of the body? SKIN ,mucus memb,urine tears ,cilia
What immunoglobulin is the first antibody in an immune response? IgM
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