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Radiology MCQ Bank Forum Hot - Unanswered
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Quick Scroll panda sign 05.15.04 (4 years ago) #1

plz tell me what is panda sign.
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Quick Scroll 05.16.04 (4 years ago) #2

Mikulicz's syndrome (uveoparotid fever) is characterized by parotid, lacrimal, and bilateral salivary involvement. The disorder produces a characteristic gallium pattern referred to as the "Panda sign" (due to lacrimal, parotid, and physiologic nasophrayngeal Ga-67 activity). The Panda sign can also be seen in sarcoid patients without uveoparotid syndrome- in fact, it can be seen in up to 80% of patients with Stage I disease . The panda sign can be seen in 4% of patients without sarcoid including lymphoma, Sjogren syndrome, and HIV .

Panda sign: Marked parotid and lacrimal uptake of gallium in this patient with sarcoid produces the classic "Panda" sign (picture). In the chest, there is bilateral hilar and right paratracheal adenopathy, as well as active lung disease.

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Quick Scroll 05.16.04 (4 years ago) #3

a DOUBLE PANDA SIGN is seen in wilson's disease
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Quick Scroll 05.16.04 (4 years ago) #4

for the uninitiated, here is how a panda looks like

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Quick Scroll 05.16.04 (4 years ago) #5

thanks rxpg team
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Quick Scroll 06.14.04 (4 years ago) #6

There is another condition producing "Panda Sign" or "Racoon Eye Sign"

Any Guesses icon_question.gif

I will tell the answer tomorrow
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Quick Scroll to dr.Bruno 06.14.04 (4 years ago) #7

Aqueduct lesion,
Although a diverse group of lesions may affect the aqueduct, intrinsic abnormalities of its surrounding structures and in particular of the quadrigeminal plate have a quite limited differential diagnosis. Neoplastic expansive lesions are usually gliomas, lymphomas only occasionally involving the quadrigeminal plate. Non-neoplastic abnormalities include cavernous angiomas, demyelinating diseases and infarcts. Neurosarcoidosis is commonly found in the periaqueductal region and may also involve the pineal gland (see pineal region tumour). Mesencephalic involvement can be characteristic in Wilson's disease where the so-called "face of the giant panda" sign is observed, consisting of high signal throughout the mesencephalon except for sparing of the red nucleus and the lateral portion of the pars reticulata of the substantia nigra and a portion of the superior colliculus. Abnormalities of the quadrigeminal plate ranging from slight loss of the normal intercollicular separation through collicular fusion to a markedly elongated, beak-shaped tectum are observed in Chiari II malformation. Histological changes of gliosis and neurofibrillary tangles manifesting on MR imaging as periaqueductal T2 hyperintensities are observed in supranuclear palsy and they have been demonstrated to correlate well with the severity and duration of the disease.
Expansive lesions of the structure surrounding the aqueduct may present clinically with triventricular hydrocephalus. MR is the technique of choice (Fig.1). The morphological deformations of the quadrigeminal plate are best viewed on sagittal images and signal abnormalities are best depicted on T2-weighted sequences. 8) icon_lol.gif
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Quick Scroll 06.14.04 (4 years ago) #8

RACOON'S EYE SIGN that is periorbital ecchymosis is seen in fracture basillar skull. (harrison-2435)

Dear bruno is panda's sign & racoon's eye sign r the same?
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Quick Scroll Bassl skull fracture 06.14.04 (4 years ago) #9

Skull Fractures
A simple linear skull fracture often requires no intervention. If the fracture crosses the groove of the middle meningeal artery or venous sinuses, hospitalization for observation is appropriate. A skull fracture that is depressed a distance greater than the thickness of the skull often needing surgical elevation. This rarely requires emergency surgery, however, and can frequently be delayed until full consciousness regained. A basilar skull fracture is often marked by hemotympanum, Battle's sign (ecchymosis behind the ear), 'raccoon eyes' (periorbital ecchymosis), and CSF otorrhea or rhinorrhea.
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Quick Scroll 06.14.04 (4 years ago) #10

Bilateral ‘black eyes’ without direct trauma, is a fairly certain sign of an anterior fossa fracture in Skull injuries: Panda sign.
Bilateral periorbital haematoma is the cause for the formation.
Ref: Bailey & Love 22nd Ed. ,Page: 398, also fig.28.26
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