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Quick Scroll complement deficiencies 07.23.05 (3 years ago) #1
COMPLEMENT
Factor H deficiency - HUS
C3 decreased - factor I deficiency, C3 def, SLE, IE, MCGN
C5678 def - Neisseria infection
C4 decreased - Hep C (cryoglobinaemia)
C1qrs, C2, or C4 decreased - SLE

Decreased complement-regulating surface proteins, including the decay-accelerating factor (DAF) or CD55, homologous restriction factor (HRF) or C8 binding protein, and membrane inhibitor of reactive lysis (MIRL) or CD59 -paroxysmal nocturnal hemoglobinuria

C1inh def - hereditary angioedema(treatment-FFP; prevention-danazol,aminocaproic acid
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