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manpreet108Send an Instant Message to manpreet108  




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Quick Scroll gyne -ovarian mass 07.25.05 (3 years ago) #1

4x4 cm ovarian mass in a post menopausal women .m/t is -
1.wait and watch .
2.surgical exploration
3prog pills
4clomiphene therapy.

pls rep with reasons.
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Quick Scroll 07.26.05 (3 years ago) #2

the question framed is of very broad terms. thus considering to be the common condition which is simple ovarian cyst.

then any mass less then 5 cm u should go for wait and watch with serial usg evaluation.
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Quick Scroll 07.26.05 (3 years ago) #3

There have been different ultrasound scoring systems to try to predict malignancy. Anytime the ultrasonographer sees the following characteristics, there may be an increased chance of malignancy beyond just a simple cyst:
    multiloculated cysts (septations within a cystic area)
    solid areas
    bilateral lesions
    ascites (fluid in the pelvic/abdominal cavity)
    evidence suspicious for intraabdominal metastases


Giving a score of one for any of the above findings, the risk of malignancy cases were divided into :
Risk of Malignancy by Ultrasound Findings
Ultrasound score-------Benign--------Malignant
--------------------------(n=290)-------(n=75)
0-------------------------79 (27%)------3 (4%)
1-------------------------12 (39%)------13 (17%)
2-5-----------------------99 (34%)------59 (79%)
Note that many (34%) benign masses have more than one characteristic of malignancy.

When does the chance of ovarian cancer increase enough that it is best to have the initial surgical exploration done by a gynecologic cancer surgeon specialist?

The authors in the Risk of Malignancy study used a scoring system by Jacobs (1990) based on the menopausal status (premenopausal = 1, postmenopausal = 3), ultrasound characteristics (zero or one characteristic ultrasound finding = 1, two or more features = 3) and the CA-125 level (actual value). They then multiply these three values together (RMI= M X U X Ca-125). For example, a postmenopausal woman (3) who had two ultrasound characteristics of malignancy (3) and had a CA-125 level of 50 u/ml, would have a risk of malignancy index (RMI) of 3x3x50 =300. In calculating RMIs for all the patients in their study, Tingulstad et al found a cutoff of RMI=300 which is used to predict whether there may be a malignancy present, if the RMI is 300 or over, 3 out of 4 times an ovarian malignancy will be present.

In this case without USG findings and CA-125 findings it would be impossible to predict treatment but surgical exploration would be best in the absence of above. Even a complex cyst in postmenopausal state is dangerous.
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Quick Scroll 07.26.05 (3 years ago) #4

i think it shud b wait & watch coz no symptoms r mentioned& u cant go4 surgery with investigations so its relatively a better choice
opinions???
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Quick Scroll 07.26.05 (3 years ago) #5

thats a perfect explanation i was looking for ....thanks chand.

the ans given in guides is wait and watch but i wd go for surgicall exploration-with the detailed analysis mentioned .
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Quick Scroll 07.26.05 (3 years ago) #6

funtional cysts in ovary are less than 7 cm in size and they regress spontaneouly ...
but also note that size is not a criterion to evaluate malignant potential in a post menopausal women because OVARIES ARE NON FUNCTIONAL.

this was told in gyne lectures in UG.
the reason is very clear with the grading system quoted in the above extract.
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