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Quick Scroll gyne -krukenberg tumor 07.25.05 (3 years ago) #1

all r true about krukenberg tumor except-
1.B/L
2 enlarged ovaries
3.cystic areas in ovaries
4sigent ring on H/E
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Quick Scroll 07.26.05 (3 years ago) #2

ovaries retain normal shape.........
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Quick Scroll 07.26.05 (3 years ago) #3

The Krukenberg tumor is named after Friedrich Ernst Krukenberg (1871-1946), a German doctor who first described them as "fibrosarcoma ovarii mucocellulare carcinomatodes".

A Krukenberg tumor is the name given to tumors of the ovaries. Although they may appear to be a primary tumor of the ovary, are always a metastasis (i.e. a secondary tumor) which has spread from a malignant tumour in another site. Krukenberg tumors are often found in both ovaries. Microscopically, they is characterized by appearance of mucin-secreting signet-ring cells in the tissue of the ovary; when the primary tumor is discovered, the same signet-ring cells will be found.

Although a Krukenberg tumor is most commonly a metastasis from a gastric cancer (usually an adenocarcinoma), this is not always the case. Other tumours of the gastrointestinal tract (including, significantly, colon cancer) have been known to cause Krukenberg tumours, and recent case-reports of Krukenberg tumors originating from tumors of the tip of the appendix have appeared in the medical literature.

In young patients, krukenberg's tumor may be mistaken for granulosa cell tumor or lipid rich tumor

Gross: multinodular enlargement of ovaries, bilateral



Metastatic tumors to ovary are uncommon, but there is one situation in which a metastatic adenocarcinoma to ovary appears as a large mass and resembles a primary tumor: a so-called "Krukenberg" tumor of ovary which has a signet ring histologic pattern and usually is metastatic from a primary in gastrointestinal tract. Seen here extending out of the pelvis at autopsy is a large right ovarian mass. Metastases are also present in the lower right portion of liver.

Micro: mucin-producing signet-ring cells; may have tubular pattern that resembles Sertoli-Leydig tumor; must see intracytoplasmic mucin; tumor emboli common; may have marked stromal proliferation with storiform growth and variable luteinization

All the four choices are correct, may be the confusion arose with the line in shaw that ovaries maintain their shape but did not mention size. There are lots of cases as mentioned in your previous post where the size has shown to be increased. And regarding the cystic spaces it is very mentioned in Shaw itself.
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Quick Scroll 07.26.05 (3 years ago) #4

so its 2
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Quick Scroll 07.26.05 (3 years ago) #5

but here if we hav to go for one....we will go for 2 na coz this is the most dicey option rest of others being confirmed ??
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