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Quick Scroll bone metastasis 08.27.05 (3 years ago) #1

Therapies targeting which of the following mediators of bone metastases are likely to influence osteoclastogenesis?

a. RANKL
b. BMP
c. ET-1
d. None of the above
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Quick Scroll 08.27.05 (3 years ago) #2

It is RANKL (Receptor Activator of Nuclear factor kappa B ligand) along with RANK (Receptor Activator of Nuclear factor kappa B) and Osteoprotegerin
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Quick Scroll 09.30.05 (3 years ago) #3

RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis
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