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salman · Credits: 353 My Scrapbook

hallo
here r som eof my state Qs which none could givesatisfactoryans . I shall be grateful if any1 is able 2 put an openion

1) doc for migraine----------a)ergometrine
b)sumatriptan

2)absolute contraindication for chemotherapy---
--a)septicemia
b)pregnancy
c)morbid ill patient
d)all of the above

3)ototoxicity with frusemide is increased by-------
a)ampicillin
b)gentamicin
c)ciprofloxacin
d)mefloquine
CIAO

4)malignant neuroleptic syndrome seen in;
a)amoxapine
b)doxapine
c)imipramine
d)selegelline

5)which hormone is M.Imp for growth?---------thyroid/GH/insulin

pilgrim · Credits: 947 My Scrapbook

increased ototoxicity with
gentamicin definitely..with aminoglycosides

pilgrim · Credits: 947 My Scrapbook

In acute migraine , the drug of choice is sumatriptan.....although textbooks are unclear...
I can direct you to a site which says that for a fact

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pilgrim · Credits: 947 My Scrapbook

Q4
Malignant neuroleptic syndrome is seen in
AMOXAPINE
Although it is not a neurolept drug....
it causes the syndrome because of the action that causes The syndrome
DOPAMINE blockade

doctorgirl78 · Credits: 5336 My Scrapbook

Your choices are all TCA which will enhance amine levels and mostly don’t affect dopamine uptake

Selegilline MAOi also enhances amin levels

NMS is due to antidopaminergic effects of neuroleptics that is why bromocriptine is the DOC………..
amoxapine is unique in having antidepresant and neuroleptic properties.read latest tripathi...........blocks D2 receptors hence the choice

salman · Credits: 353 My Scrapbook

thanks docgirl/Pi....
rest of the qs dealt

**Chemotherapy--contra---severely ill pts(as immunity depresed);;;others ---antibiotics used in septicemia;;pregnancy 2nd &3rd trimestar- can be given but better 2 avoid;
**suma -better tolerated (tripathi)
**growth -adults--GH

**if u don't have harri15 still, get a copy of CD-harri15.from the T.T. player or ur any friend

jayanta · Credits: 34967 My Scrapbook My Reading List 45 Books

VERY GOOD DISCUSSION.

shalabhsaxena · Credits: 5469 My Scrapbook

One additional point regarding Migraine
It is given in the form of NASAL spray, but it acts best only to abort the onset of acute attack of migraine, ie at aura phase of classical miraine once the attack is sets in , the sumitriptan is of no use . hence the tt of choice of acute attacks of migraine is ergotamine + NSAIDS.
It is very controversial issues , but all MCQs guides gives answer as Sumit...
but the standard text books says somthing else.

Bruno Sir what is your opinion ?????.

vivek_patel · Credits: 2336 My Scrapbook

sumitriptan
all of the above
genta
amoxapine

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