Page 1 of 2: path---in diffuse calcification of pancreas

lazybonezzz · Credits: 54735 My Scrapbook

calcium lies in---
1acinar tissues
2interstitium
3pancreatic ducts
4anywhere

lazybonezzz · Credits: 54735 My Scrapbook

hronic pancreatitis can be classified into 3 categories: (1) chronic calcifying pancreatitis, (2) chronic obstructive pancreatitis, and (3) chronic inflammatory pancreatitis.

Chronic calcifying pancreatitis is invariably related to alcoholism. The earliest finding is precipitation of proteinaceous material in the pancreatic ducts that forms protein plugs that subsequently calcify. The ducts and lobules are initially involved in a random manner, and they are surrounded by normal parenchymal tissue. However, as the disease progresses, these normal areas become more diffuse. The pancreatic ductal epithelium undergoes atrophy, hyperplasia, and metaplasia at the site of the protein plugs. Many of the small pancreatic ductules dilate, while others are obliterated by fibrosis.

The main pancreatic duct shows a chain-of-lakes appearance due to alternating stenoses and dilatation. In approximately one half of patients with chronic calcific pancreatitis, the pancreatic parenchyma contains cysts of varying sizes (several millimeters to 5 cm). These cysts are lined by cuboidal epithelium and contain pancreatic enzymes. Peripancreatic fibrosis is usually a late finding that involves the portal and/or splenic veins. Peripancreatic fibrosis causes stenosis or occlusion of retroperitoneal lymph channels. Ascites may complicate chronic calcific pancreatitis as a result of portal hypertension or lymphatic obstruction in 1-2% patients.

lazybonezzz · Credits: 54735 My Scrapbook

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lazybonezzz · Credits: 54735 My Scrapbook

Pancreatic calcifications are a common finding on plain films of the abdomen and are detected in 2559% of patients. Calcifications in chronic pancreatitis are mainly intraductal stones located either in the main pancreatic duct or in side branches. They are punctiform or coarse and may have a focal, segmental or diffuse distribution.

bhavu · Credits: 9491 My Scrapbook

ya it should be pancreatic ducts

BRAVO · Credits: 46105 My Scrapbook

hey lazy tussi great ho yaar sawaal bhi poochte ho aur jawab bhi dete ho!!!

lazybonezzz · Credits: 54735 My Scrapbook

well this extract is bout calcification in chronic pancreatitis
this Q is bout diffuse & the last line says theyr mainly intraductal but their distribution can b diffuse---thats diffusely in the ducts???
ans given is all

bhavu · Credits: 9491 My Scrapbook

yes i found out.

see what harrison 15th edipage 1800 says,the radiographic hall mark of chronic pancreatitis is the presence of scattered calcification throughtout the pancreas. diffuse pancreatic calcification indicates that significant damage has occured and obviates the need for a secretin test

lazybonezzz · Credits: 54735 My Scrapbook

u rock bhavu!
thanx ans given is 4

decembermist · Credits: 41211 My Scrapbook

In Dr.Salgunan 's book its c)

Now its clear tht ans is d) anywhere

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