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RxPG :: View topic - Risk of development of Chorio Carcinoma  
Gyn Obs MCQ Bank Forum Hot - Unanswered
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rkrai11Send an Instant Message to rkrai11  




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Quick Scroll Risk of development of Chorio Carcinoma Thursday 22nd of September 2005 11:20:22 PM (4 years ago) #1

Risk of development of chorio carcinoma is maximum after:
1. Spontaneous abortion
2.H.Mole
3.Full term pregnancy
4.Pre-term pregnancy
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Quick Scroll Friday 23rd of September 2005 07:29:38 AM (4 years ago) #2

At significantly higher risk:
Risk for the development of a hydatidiform or invasive mole or choriocarcinoma include:
    a prior mole (30 times the risk)
    maternal age greater than 40 years (5 times) or less than 20 years (1.5 times)
    a previous spontaneous abortion (twice the risk)


At slightly lower risk:
Eating a diet high in vitamin A and having one or more children without having a previous abortion is statistically correlated with a lower than average risk of developing a complete mole.

Choriocarcinoma most frequently follows a previous complete hydatidiform mole (50%), though 25% may follow a normal pregnancy or spontaneous abortion.
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rkrai11Send an Instant Message to rkrai11  




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Quick Scroll Friday 23rd of September 2005 08:56:21 PM (4 years ago) #3

Chand22sg! Any Reference of these data please.
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Quick Scroll Thursday 15th of June 2006 09:02:04 AM (3 years ago) #4

full term pregnancy
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faizySend an Instant Message to faizy  




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Quick Scroll Tuesday 18th of July 2006 01:58:14 AM (3 years ago) #5

answer is
FULL TERM PREGNANCY
high risk conditions are

-hcg titre > 40,000 iu/l
-durations of symptoms >4 months
-metastasis to liver ,lungs
-falied previous chemotherapy following term pregnancy.
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Quick Scroll Thursday 1st of November 2007 06:09:17 PM (2 years ago) #6

Hi all,
according toOHCS(oxford series of clinical secialities)
50% of choriocarcinoma follows a benign mole
20%follow abortions
10% follow normal pregnancy.
so ans here is H.MOLE
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Quick Scroll Friday 2nd of November 2007 05:47:59 PM (2 years ago) #7

Linky wrote:
Hi all,
according toOHCS(oxford series of clinical secialities)
50% of choriocarcinoma follows a benign mole
20%follow abortions
10% follow normal pregnancy.
so ans here is H.MOLE
hi. looks like a lot of discussion going on about GTDs[gestational trophoblastic disease]
between one half & 2/3rds of malignant GTDs follow evacuation of a complete or partial mole.in that 50-70% are invasive moles & 30-50% are chorioca.PSST can follow any pregnancy event.
chorioca is 1000 times more likely to follow a mole than normal pregnancy.the risk is much higher with a complete mole than a partialmole.
ref:COG vol46, number3,547-554
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Quick Scroll Thursday 22nd of November 2007 08:44:09 PM (2 years ago) #8

AFTER HYDATIDIFIOF MOLE
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shivaniswarnaSend an Instant Message to shivaniswarna  




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Quick Scroll Thursday 14th of February 2008 11:50:10 AM (2 years ago) #9

max risk is after a molar pregnany.if it were a full term pregnancy,then the incidence of choriocarcinoma would have been very high.
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Quick Scroll Friday 28th of March 2008 07:35:38 AM (1 year ago) #10

ChorioCa: 50% from GTD, 25% from ectopic, miscarrige, 25% from norm pregnancy. (Kaplan 2001)
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dr_nidhiSend an Instant Message to dr_nidhi  




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Quick Scroll Friday 11th of April 2008 09:44:08 PM (1 year ago) #11

the risk for developing choriocarcinoma is maximum after term pregnancy. The WHO risk scoring for gestational trophoblastic disease gives a score 4 if prior pregnancy is term and a score 0 if its a molar pregnancy.A gestational trophoblastic neoplasia following term pregnancy is most likely to be a choriocarcinoma.
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Quick Scroll Thursday 5th of June 2008 12:14:36 PM (1 year ago) #12

risk of choriocarcinoma is 50% foll evacuation of a hydati mole,25% foll an abortion ,20% foll fullterm labour and 5%after extrauterine preg.trophoblastic ds foll a full term preg is always a chorioca but that foll an abortion or a molar preg might be chorioca or an invasive mole
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