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NEHRA
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AGRANULOCYTOSIS?
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09.25.05 (3 years ago)
#1
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WHICH ONE DOESN'T CAUSE AGRANULOCYTOSIS?
A. Chloramphenicol
B. Indomethacin
C. Tolbutamide
D. Captopril
E. Nitrofurantoin
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shraddha
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09.25.05 (3 years ago)
#2
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is it captopril
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drada
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aganulositosis
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09.25.05 (3 years ago)
#3
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 a very long list available @worldmedicine.orgform the probability list ans is Chloramphenicol!!!
Note that ACE 1 inhibitors hav got significant risk....COMMON agents causing aganulositosis
1,anti neoplastic drugs
2,SEMI synthetic penicillin
3,NSAIDs
4,Phenothiazines
5,Sulfonamides
6,BZDs
7,Barbiturates
8,Gold
and9, antiTHYROIDs
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NEHRA
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Aganulocytosis list of drugs
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09.25.05 (3 years ago)
#4
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These are the drugs causing agrnulocytosisAprindine
Captopril
Carbimazole
Cefotaxime
Chloramphenicol
Co-trimoxazole
Cytotoxics
Gold salts
Indomethacin
Methimazole
Oxyphenbutazone
Phenothiazines
Phenylbutazone
Propylthiouracil
Sulfonamides
Tolbutamide
Tricyclic antidepressants
If there is any other drug kinly let me know.
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shraddha
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09.26.05 (3 years ago)
#5
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so what's the answer
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drada
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09.26.05 (3 years ago)
#6
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It is true that most of the drugs can result in agranulocytosisBut chloramphenicol comes in the bottom of probability list& hence the answer..
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NEHRA
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09.26.05 (3 years ago)
#7
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answer is nirofurantoin
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drada
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09.26.05 (3 years ago)
#8
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hey,why u r still saying that ans is nitrofurentoin and not chloramphenical...pls give some reference....
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NEHRA
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I have given full list yaar.Then why getting confused.
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09.27.05 (3 years ago)
#9
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These are the drugs causing AGRANULOCYTOSIS
Aprindine
Captopril
Carbimazole
Cefotaxime
Chloramphenicol
Co-trimoxazole
Cytotoxics
Gold salts
Indomethacin
Methimazole
Oxyphenbutazone
Phenothiazines
Phenylbutazone
Propylthiouracil
Sulfonamides
Tolbutamide
Tricyclic antidepressants
If there is any other drug kindly let me know.
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shraddha
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09.27.05 (3 years ago)
#10
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Hematologic reactions, specifically granulocytopenia(sore throat and fever); leukopenia (sore throat and fever); megaloblastic anemia(unusual tiredness or weakness); or thrombocytopenia (rarely, unusual bleeding or bruising; black, tarry stools; blood in urine or stools; pinpoint red spots on skin)
this is what i found for nitrofurantoin
The hematologic toxicity of chloramphenicol can manifest itself in 1 of 2 ways¾either as a reversible bone marrow depression or an idiosyncratic aplastic anemia. Bone marrow depression is dose-related and most commonly seen when serum concentrations exceed 25 mcg/mL. Bone marrow changes are usually reversible when chloramphenicol is discontinued
this for chloramphenicol
why can't
the ans be tolbutamide
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