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Quick Scroll Humoral graft rejection is characterised by- 10.11.05 (3 years ago) #1
Humoral graft rejection is characterised by-

a) Intense mononuclear infiltration
b) Neovascularisation of grafted tissue
c) Thrombosis of the blood vessels and ischemic necrosisd) Monocytic infiltration ??????
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Quick Scroll 10.11.05 (3 years ago) #2
Thrombosis of the blood vessels and ischemic necrosis!
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Quick Scroll 10.11.05 (3 years ago) #3
is there any kind of infiltration in it?
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Quick Scroll 10.11.05 (3 years ago) #4
acute humoreal graft rejection is also known as rejection vasculitis.
mediated primarily by anti donor anti bodies and hence it is manifested mainly by damage to the blood vessels. this may take the form of necrotizing vasculitis with endothelial necrosis, neutrophilic infilteration, depostion of igs,complements, fibrin and thrombosis. such lesions are associated with extensive necrosis of the renal parenchyma.

In many cases the vasculiti is less acute and is charectrised by marked thickening of intima with proliferation of fibroblasts,myocyes and foamy macrophages.

and in chronic rejection mononuclear cell infilteration with thrombosis is seen seepage 220-221 robbins 7th edi
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