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drprasuSend an Instant Message to drprasu  




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Quick Scroll anesthesia - circumcision 10.12.05 (3 years ago) #1

regarding circumcision which one is true: AIIMS MAY 2003

1) should be done without anes. as it is hazardous to give anesthesia
2) should be done without anes. as neonate do not feel pain as adult
3) should be done under local anesthesia only
4) general anes. should be given to neonate for circumcision as they also feel pain as adult.
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Quick Scroll 10.13.05 (3 years ago) #2

Efficacy and Safety of Lidocaine–Prilocaine Cream for Pain during Circumcision

ABSTRACT

Background Neonatal circumcision is a painful surgical procedure often performed without analgesia. We assessed the efficacy and safety of 5 percent lidocaine–prilocaine cream (Emla) in neonates undergoing circumcision.

Methods We carried out a double-blind, randomized, controlled trial in 68 full-term male neonates: 38 were assigned to receive lidocaine–prilocaine cream, and 30 to receive placebo. One gram of lidocaine–prilocaine or placebo cream was applied to the penis under an occlusive dressing for 60 to 80 minutes before circumcision. Behavioral (facial activity and time spent crying) and physiologic (heart rate and blood pressure) responses were recorded during the procedure. Blood samples were obtained at various times after drug application for measurements of methemoglobin and plasma lidocaine, prilocaine, and o -toluidine (a metabolite of prilocaine).

Results A total of 68 and 59 neonates were included in the safety and efficacy analyses, respectively. Demographic characteristics such as gestational age and birth weight did not differ between the lidocaine–prilocaine and placebo groups. During circumcision, the neonates in the lidocaine–prilocaine group had less facial activity (P = 0.01), spent less time crying (P<0.001), and had smaller increases in heart rate (P = 0.007) than the neonates in the placebo group. Facial-activity scores were 12 to 49 percent lower during various steps of the procedure in the lidocaine–prilocaine group. As compared with neonates in the placebo group, infants in the lidocaine–prilocaine group cried less than half as much and had heart-rate increases of 10 beats per minute less. Blood methemoglobin concentrations (expressed as a percentage of the hemoglobin concentration) were similar (1.3 percent) in both groups. Lidocaine and prilocaine were detected in plasma in 23 (61 percent) and 21 (55 percent) of the infants treated with lidocaine–prilocaine cream, respectively.

Conclusions Lidocaine–prilocaine cream is efficacious and safe for the prevention of pain from circumcision in neonates.

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Quick Scroll 10.14.05 (3 years ago) #3

question has option of local anesthetic but with "ONLY" word added in the end. local anesthesia may be the best but surely it is not the ONLY one.
LEE 12/e says general anesthetics are generally
prefered for circumcision in neonate and local is given as alternative.
in option 3 if "only" had not been given, it surely would have been the answer.
i think best answer is 4
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Quick Scroll 10.14.05 (3 years ago) #4

i agree with u drprasu!!!!!
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Quick Scroll 10.28.05 (3 years ago) #5

AGREE WITH OPTION 4
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