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Quick Scroll PSM -leprosy.cansomeone answera this please.......... 10.22.05 (3 years ago) #1

in a pt of paucibacillary leprosy takin multidrug therapy since last 6 mnths,comes with persistment erythema and induraton of the plaque...accordin to WHO what is the best line of treatment...
a)continue dapsone for another 6 mnths
b)stop the treatment icon_rolleyes.gif
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Quick Scroll 11.07.05 (3 years ago) #2

continue dapsone for 6months
u can refer that in park PSM also
take care bye
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Quick Scroll 11.11.05 (3 years ago) #3

In india MDT is given until lesions are cleared completely as given in Park but ACCORDING TO WHO.. answer is 'Stop the treatment'. U can refer any WHO document.. The lines given are..

In PB patients, it is assumed that 6 months of treatment with RFP alone can ensure a complete clearing of the bacteria. However, to prevent RFP resistance dapsone has been added. The attainment of clinical inactivity should not be the condition guiding the continuation of MDT in PB patients, because these patients are virtually always cleared of viable bacteria in 6 months with the WHO-MDT regimen. Hence, one should keep in mind that clinical activity in PB leprosy does not necessarily directly correlate with bacterial multiplication. In a substantial proportion of patients, clinical inactivity may not be achieved in 6 months even after a complete clearing of the organisms. Follow-up studies of PB patients in MDT's field trials have shown that complete clearing of lesions takes 1–2 years after treatment discontinuation.
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Quick Scroll 11.11.05 (3 years ago) #4

thanks for ure correction dr
take care and have agreat day
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Quick Scroll 11.11.05 (3 years ago) #5

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Quick Scroll 11.17.05 (3 years ago) #6

thanks for these details...

any such applicability for MB leprosy??
i mean if same qn is framed --like a pt on MDT for MB leprosy for 1 yr--still has clinical activity --what is the next aproach--what are WHO guidelines?continue MDT?or stop?

pls help.
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Quick Scroll 11.18.05 (3 years ago) #7

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Quick Scroll 11.21.05 (3 years ago) #8

ans is stop the treatment in both the case...........
from the horse's mouth
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Quick Scroll 11.21.05 (3 years ago) #9

Thanx but Any refernce outofthebox??
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Quick Scroll 11.22.05 (3 years ago) #10

hi i think u should continue trtmnt and treat erythema simulstaneously...... send for skin ref.
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