Page 1 of 1: Therapeutic index of a drug is an indicator of

drmeenakshidua · Credits: 492 My Scrapbook

Q4. Therapeutic index of a drug is an indicator of
a. Potency
b. Safety
c. Toxicity
d. Efficacy
(why can’t it be safety .. why toxicity everywhere as ans )

doctorgirl78 · Credits: 5514 My Scrapbook

trip uses the word safety margin synonymous with therapeutic index...so i could go with it too

BRAVO · Credits: 46105 My Scrapbook

ya it shud be safety!!!

thakurda · Credits: 1233 My Scrapbook My Reading List 42 Books

therapeutic index = LD50/ED50 and is a measure of toxicity of a drug

ash123 · Credits: 336 My Scrapbook

therapeutic index gives the limits of the safety of the drug

drparveen · Credits: 775 My Scrapbook My Reading List 7 Books

safety of the drug

nargis · Credits: 2485 My Scrapbook

iT IS SAFETY.

dranush1 · Credits: 1295 My Scrapbook

"therapeutic index" refers to a quantitative measure of the selectivity of a drug when a therapeutic effect ("E") and a toxic effect ("T") are being compared. The therapeutic index can then be calculated as ED.sub.50/TD.sub.50, at some arbitrary level of response observed in a subject receiving the drug. The ED.sub.50 is the dose required to generate the desired intensity of therapeutic effect in 50% of the subjects tested. The TD.sub.50 is the dose required to generate the toxic effect in 50% of the subjects tested.

The therapeutic index is a useful indicator of the benefit versus adverse effect of a drug. Those drugs which have a high therapeutic index can be administered over a wide range of effective doses without incurring significant adverse events. Conversely, drugs having a small therapeutic index can be administered over a small range of effective doses without incurring significant adverse events.

so guys answer is of your choice,.............

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