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ardySend an Instant Message to ardy  




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Quick Scroll medicine 12.27.05 (3 years ago) #1
a 43 YR old man wth microscopic polyarteritis acutely develops renal failure wth oliguria and hematuria.lab examination reveals P ANCA ab.which of the following histologic changes is found
a. eosinophilic masses were attached to capsule of bowmans space
b.fibrinoid necrosis present in aff arteriole
c.large no of neutrophils were seen in interstitium & tubules
d.numerous crescent were present in glomeruli
ans is given d
why nt b?
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Quick Scroll 12.27.05 (3 years ago) #2
Cause in RPGN.....we get cresents and the injury is due to ANCA.........
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Quick Scroll 12.27.05 (3 years ago) #3
this is a case of idiopathic renal limited crescentic glomerulonephritis
ANCA Ig are detected.
so the ans is (d)
ref harrison 15th ed
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Quick Scroll 12.27.05 (3 years ago) #4
i thought it to be PAN/Microscopic polyangitis (fibrinoid necrosis). due to p anaca
bt it would never present wth renal failure,so the ans is post streptococcal gn .
thanx morpheus and shaina!
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Quick Scroll 12.27.05 (3 years ago) #5
shaina wrote:
this is a case of idiopathic renal limited crescentic glomerulonephritis
ANCA Ig are detected.
so the ans is (d)
ref harrison 15th ed

bt one doubt how do we rule out microscopic polyangitis(a/w fibrinoid necrosis )panca association 70% it presents acutely wth glomerulonephritis ,haematuria,renal failure!
plz explain. icon_eek.gif
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Quick Scroll 12.28.05 (3 years ago) #6
icon_question.gif icon_question.gif icon_eek.gif ,anybody?
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