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Quick Scroll Nagging question 05.09.06 (2 years ago) #1

how is alpha-fetoprotein produced in hepatocellular CA?
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Quick Scroll 05.10.06 (2 years ago) #2

Alpha-fetoprotein

* Alpha-fetoprotein is a normal fetal serum protein produced by the yolk sac and liver
* Progress increases in serum levels are seen in 70-90% of patients with HCC
* Slightly increased and often fluctuating serum levels also seen in hepatitis and cirrhosis
* In HCC serum levels correlate with tumour size
* Rate of increase in serum levels correlate with growth of tumour
* Tumour resection results in a fall in serum concentrations
* Serial assessment useful in measuring response to treatment
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