Page 1 of 3: BIOCHEMISTRY

paddy241981 · Credits: 1628 My Scrapbook

[/b]Coproporphyrin III is
a. Normal hemoglobin breakdown product
b. Abnormal hemoglobin precursor
c. Excreted in lead poisoning
d. Excreted in hepatic porphyria

determineddoc · Credits: 3359 My Scrapbook My Reading List 2 Books

i guess it is excreated in hepatic porphyrias.

paddy241981 · Credits: 1628 My Scrapbook

but is it not excreted in lead poisoning

hummingbird · Credits: 1319 My Scrapbook

even i think d ans s 3ed otion.its excreted in lead poisoning

blitzkrieg · Credits: 305 My Scrapbook

the answer is :- excreted in lead poisoning

blitzkrieg · Credits: 305 My Scrapbook

Ref : pg 278 Harper's Biochemistry 26th ed

paddy241981 · Credits: 1628 My Scrapbook

THANKS GUYS

golay · Credits: 513 My Scrapbook

advice on books to read?

shravani · Credits: 6427 My Scrapbook

A chronic alcoholic develops severe memory loss with marked confabulation. Deficiency of which of the following
vitamins would be most likely to contribute to the neurologic damage underlying these symptoms?

A. Folic acid

B. Niacin

C. Riboflavin

D. Thiamine

E. Vitamin B12

shravani · Credits: 6427 My Scrapbook

Explanation:

The correct answer is D. Wernicke-Korsakoff syndrome refers to the constellation of neurologic symptoms
caused by thiamine deficiency. Among these, a severe memory deficit, which the patient may attempt to cover
by making up bizarre explanations (confabulation), is prominent. Anatomical damage to the mamillary bodies
and periventricular structures has been postulated as the cause. In the U.S., severe thiamine deficiency is seen
most commonly in chronic alcoholics. Thiamine deficiency can also damage peripheral nerves ("dry" beriberi)
and the heart ("wet" beriberi).

Folic acid deficiency (choice A) produces megaloblastic anemia without neurologic symptoms.

Niacin deficiency (choice B) produces pellagra, characterized by depigmenting dermatitis, chronic diarrhea, and
anemia.

Riboflavin deficiency (choice C) produces ariboflavinosis, characterized by glossitis, corneal opacities,
dermatitis, and erythroid hyperplasia.

Vitamin B12 deficiency (choice E) produces megaloblastic anemia accompanied by degeneration of the
posterolateral spinal cord.

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