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drsmita_s
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Anaesthesia
:which local anaesthetic
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05.25.06 (2 years ago)
#1
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which local anaesthetic is a vasoconstrictor?
a) lignocaine
b) procaine
c) bupivacaine
d) ropivacaine
ans given is ropivacaine. as far as my knowledge goes, cocaine is the only vasoconstrictor LA. what do you say?
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malu8
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05.25.06 (2 years ago)
#2
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I think all local anaesthetics r vasodilators except cocaine
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legaldevil
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hi
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05.25.06 (2 years ago)
#3
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A local anesthetic is a drug that reversibly inhibits the propagation of signals along nerves. When it is used on specific nerve pathways, effects such as analgesia (loss of pain sensation) and paralysis (loss of muscle power) can be achieved.
While many other drugs have some local anesthetic action as a side effect, all substances that are clinically used belong to two related classes: aminoamide and aminoester local anesthetics. These so-called synthetic local anesthetics are structurally related to cocaine. They differ from cocaine mainly in that they have no abuse potential and do not act on the sympathoadrenergic system, i.e. they do not produce hypertension or local vasoconstriction.
Local anesthetics in clinical use
Amino esters
Benzocaine
Chloroprocaine
Cocaine
Procaine
Amino amides
Bupivacaine
Levobupivacaine
Lidocaine
Mepivacaine
Prilocaine
Ropivacaine
Combinations
lidocaine/prilocaine (EMLA)
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drsmita_s
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05.25.06 (2 years ago)
#4
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thanx malu8 and legaldevil,
this is exactly what i'm trying to say. so, according to u the answer to this question is none of the above.
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doctor_spupadhyay
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06.04.06 (2 years ago)
#5
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answer is cocaine.
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johnserif
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04.02.07 (1 year ago)
#6
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ropivacain at papers, but I didn't saw any hypertension
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nabrina
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Re: <a href=
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04.02.07 (1 year ago)
#7
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| drsmita_s wrote: |
which local anaesthetic is a vasoconstrictor?
a) lignocaine
b) procaine
c) bupivacaine
d) ropivacaine --> THE ANSWER
ans given is ropivacaine. as far as my knowledge goes, cocaine is the only vasoconstrictor LA. what do you say? |
The answer is Right .
“Ropivacaine. in contrast to bupivacaine. has inherent vasoconstrictor properties that may affect its uptake. Convery et al. showed peak plasma concent rations of both agents can be within the acceptable safely ranges when injected into the knee joint.”
Ambulatory Anesthesia and Perioperative Analgesia - Page 70 (Susan M. Steele)
And barring cocaine , though it is a potent vasoconstrictor,All local anaesthetics show biphasic activity, being vasodilators at high concentrations and vasoconstrictors at low concn.(more with S-enantiomers)
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drsmita_s
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04.03.07 (1 year ago)
#8
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nice reference dr. nabrina.
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drada
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04.03.07 (1 year ago)
#9
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i thought Procaine,jus like cocaine its also ester linkedLA 
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