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Quick Scroll BIOCHEM---AIIMS dec 1998 06.20.06 (2 years ago) #1
Which of these is a conservativemutator? a.glutamic acid glutamine b.histidine-glycine c.alanine -leucine d.arginine -aspartic acid i could not get any reference or any text regarding this MCQ.ASHISH_AMIT says c is correct.please help me out.
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Quick Scroll 06.21.06 (2 years ago) #2
Conservative mutation: A change in a DNA or RNA sequence that leads to the replacement of one amino acid with a biochemically similar one. It is conservative in the sense that it is not a radical change that might, for example, stop all protein production.


in this file there is a list of consevative mutotions
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Quick Scroll 06.21.06 (2 years ago) #3
here is something useful-

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Quick Scroll 06.21.06 (2 years ago) #4
with that info,

a/c??
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Quick Scroll 06.21.06 (2 years ago) #5
do we hav to consider polarity and chg-it would be c?

only structure-a?
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Quick Scroll 06.21.06 (2 years ago) #6
hi lissa,
welcome2 Nagging
cud u pls read the forum charter & comply wit the rules of posting

also check this link---
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Quick Scroll 07.28.06 (1 year ago) #7
its a
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Quick Scroll 08.21.06 (1 year ago) #8
gooooddd
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Quick Scroll 08.21.06 (1 year ago) #9
good
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Quick Scroll 10.06.07 (9 months ago) #10
conservative mutation is one that replaces an acidic amino acid with another acidic aa, a basic aa with basic one, and a neutral aa with neutral one. Therefore the answer is C.
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