Page 1 of 3: biochemistry

mehndi · Credits: 17560 My Scrapbook

glutamate is not a precursor of
1-glutathione
2-proline
3-histidine
4-ammonia

skjeev · Credits: 8210 My Scrapbook

3-histidine could b the best guess!

1.glutathione-made by 3 amino acids[glycine,cysteine and glutamate]
2.proline is made by cyclisation & reduction reactions on glutamate.
4.ammonia is made by glutaminase acting on glutamine[not glutamate-which will b the product]

ujwals · Credits: 4860 My Scrapbook

also histidine is an essential AA----> not synthesized in body

skjeev · Credits: 8210 My Scrapbook

it is essntial only during growth

ujwals · Credits: 4860 My Scrapbook

Harper 26e gives only Arginine as nutritionally semiessential

Page no 237
Table 28–1.Amino acid requirements of humans.

Nutritionally Essential .....................Nutritionally Nonessential
Arginine1 ......................................Alanine
Histidine .......................................Asparagine
Isoleucine .....................................Aspartate
Leucine .........................................Cysteine
Lysine ...........................................Glutamate
Methionine .....................................Glutamine
Phenylalanine ................................Glycine
Threonine ......................................Hydroxyproline2
Tryptophan ....................................Hydroxylysine2
Valine ............................................Proline
.....................................................Serine
.....................................................Tyrosine
-----------------------------------------------------------------------------------
1“Nutritionally semiessential.” Synthesized at rates inadequate to support growth of children.
2Not necessary for protein synthesis but formed during posttranslational processing of collagen.

skjeev · Credits: 8210 My Scrapbook

i remember histi and argi as semi?!!

ujwals · Credits: 4860 My Scrapbook

nishanth · Credits: 1080 My Scrapbook

i think histidine is considered as semi essential in adult life its only essential in children

shravani · Credits: 6427 My Scrapbook

YUP HISTIDINE IS THE PROBABLE BESR GUESS

shravani · Credits: 6427 My Scrapbook

HERE ARE SOME QUESTIONS FOR PRACTICE...
A baby that was apparently normal at birth begins to show a delay in motor development by 3 months of age. At
one year of age, the child begins to develop spasticity and writhing movements. At age three, compulsive biting of
fingers and lips and head-banging appear. At puberty, the child develops arthritis, and death from renal failure
occurs at age 25. This patient's condition is due to an enzyme deficiency in which of the following biochemical
pathways?

A. Ganglioside metabolism

B. Monosaccharide metabolism

C. Purine metabolism

D. Pyrimidine metabolism

E. Tyrosine metabolism

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