Page 1 of 1: PAEDS- HB SWITCH

mehndi · Credits: 17550 My Scrapbook

At what gestation does the switch over from fetal to adult hemoglobin synthesis begin?

A. 30 weeks
B. 36 weeks
C. 7 days postnatal
D. 3 weeks postnatal

satansfav · Credits: 735 My Scrapbook

36 weeks

nargis · Credits: 2445 My Scrapbook

36 WKS.

tini · Credits: 1183 My Scrapbook

hey.. i remember reading somewhere (in asish gupta i guess) that switch over BEGINS at 14-16 weeks... and is completed 5 days postnatal...
so, which of the above is right..!!?

drsmita_s · Credits: 18609 My Scrapbook

starts at 36 weeks of gestation and switch over complete at 9 months postnatal.

drada · Credits: 45652 My Scrapbook My Reading List 2 Books

Three types of hemoglobin are synthesized in humans depending on the stage of development. Embryonic hemoglobin is produced before birth, fetal hemoglobin (HbF) during foetal life, and adult hemoglobin after birth. Foetal hemoglobin production is switched off soon after birth although the time of switch over is not know. Hemoglobin is structurally made up of 2 alpha and 2 non-alpha chains; in addition, HbF has 2 – gamma chains and the predominant adult blood HbA1 has 2 beta chains.

drada · Credits: 45652 My Scrapbook My Reading List 2 Books

its 36 wks only,asked twice in AIIMS

nishanth · Credits: 1080 My Scrapbook

it shud be 36

s_simit · Credits: 986 My Scrapbook

adut hb starts appering after 24th wks of gestation;
though at term 75-80% is of fetal type;
between 6-12months after birth fetal hb is completely replaced by adult type

ref: dutta {Obs }

s_simit · Credits: 986 My Scrapbook

adut hb starts appering after 24th wks of gestation;
though at term 75-80% is of fetal type;
between 6-12months after birth fetal hb is completely replaced by adult type

ref: dutta {Obs }

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