RxPG - the perfect Rx for medical Post Graduate entrance blues!
Mobile Edition | Help/Newbie? | 24/7 Support
HOT | PrePG | MCQ | DNB | Careers | Books | Colleges | Dental | DocIndia | PLAB |  USMLE  | Australia | Canada | GLOBAL | OffBeat!
Articles | Forums | MCQ Crammer | Downloads | Mnemonics | Revision Tools | Recent Shouts | All Features

RxPG :: View topic - Dna grooves  
 Page 1 of 1
Author Message


hi docs...

can someone explain to me the concept of major and minor grooves in DNA double helix???

i'm reaaly gettin confused on dis one

UNANSWERED: Topics division/frequency in final mbbs question papers?

Aim USMLE Step 1

A groove is a depression..........so on the double-helix,on the side of the molecule there is a shallow depression and a deep depression which are respectively minor and major grooves......see lipinncott[the chap on DNA].

I also remember a drug used to combat cancerous cells,the name's Dactinomycin[Actinomycin D]which lodges itself in the minor groove and stops synthesis..........


i got the point... i had read dat from lippincott....

but i read from some other sources that the groove is basically defined as an angle between glycosidic bonds.... >180 is major and <180 id minor...

this is the confusin part

Cunningham's Manual of Practical Anatomy
Completely redesigned in an attractive new format, this popular three-volume manual provides students and practitioners with a comprehensive guide to human anatomy and a dissection guide recognized throughout the world.
 Page 1 of 1
Advertisement solutions  :  Terms of service (TOS)  :  CC BY-NC-SA  

Home -> Forums -> MBBS -> Dna grooves

MBBS Community
RxPG community for 16 years
2,874 active members | 10,356 posts

Topic ID #64021
Started 13 years ago
2 contributors
3 posts | 1,079 views
Thread index Print thread Feed

Server Status: 139 pages served in last minute. Page generation time: 1.898 seconds

Site Maps: [Books] [News] [Forums] [Reviews] [Mnemonics]

sitemap - top30 - centuries - testimonials

About Us :: Disclaimer :: Contact Us :: Reporting abuse :: Terms of Services :: Privacy Policy

Advertise with RxPG!
Made in India by RxPG Medical Solutions Private Limited

"RxPG" is a Registered Trademark

Chrome Web Store YouTube Twitter LinkedIn Wikipedia Facebook