Page 1 of 2: Post the questions from NIMHANS held on 17th june 2007

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1) programmed cell death is : Apoptosis

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2) microglia : is not ectodermal in origin

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3) benzodizapine antagonist: Flumazenil

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drug that needs theurapeutic monitoring : Lithium

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1.acute pancreatitis- cause hyperparathyroidism
2.not a protein, glycopeptide, polypeptide- serotonin
3. pramepexole- d3 agonist
4.cisapride- 5ht4 agonist
5. thyrotoxicosis causes- hypokalemic periodic paralysis
6. test with high sensitivity and low specificity will have - less true negatives
7. neurolathyrism- boaa

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Hi friends

I have posted here some questions of DM /M.Ch Neuro, please join with us to discuss, and help us to add rest of the questions (even the choices).
1. In Thyrotoxicosis there is
a. Hyperkalemic Periodic Paralysis
b. Hypokalemic Periodic Paralysis
c. Normokalemic Periodic Paralysis
Ans :
2. Taysach’s is due to deficiency of
a. hexose aminidase
b. lysozomal enzyme
c. galactocerebroside
Ans :
3. Foam cells , Hepatospleenomegaly in lysozomal disorder is due to deficency of
a. sphingomyelinase
Ans:
4. In congenital toxoplasmosis all are seen except
a.chorioretinitis
b.mental retardation
c.hydrocephalus
Ans :
5. which cell is involved in LE cell phenomenon
a. neutrophil
b.eosinophil
c. RBC
Ans:
6. L’Hermittes’ sign is characteristic of
a. syringomyelia
b. tabes dorsalis
Ans:
7.Astasia Abasia is seen in
a.parkinsonism
b.delusional disorder
Ans:
8. The correct match in the following
a. ondansetron – 5HT3 agonist
b. cisapride – 5HT4 agonist
Ans: b
9. Pramipaxel is
a. dopamine agonist
b.anti malarial
Ans:
10.Prophylaxis for venous thromboembolism in leg except
a.LMWH
b.Asprin
c. elastic banding
d.IVC filter
Ans :

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20.Weight gain is not a side effect in
a. sodium valproate
b.olanzapine
c.topiramate
d.lithium carbonate
Ans:
21.Treatment for refractory SIADH
a.demeclocycline
b.carbamazepine
c.phenytoin
Ans:
22.Acute Pancreatitis is a manifestation of
a.Hyperparathyroidism
b.hyperthyroidism
c.Zollinger Ellison Syndrome
Ans:
23.Appearance of tympanic membrane in mastoiditis
a.pinkish
b.pearly white
c.dull red
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24.Maximum glucocorticoid potency is seen in
a.cortisone
b.betamethasone
c.dexamethasone
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25.In mammals,DNA synthesis occurs in which part oc cell cycle
a.S phase
b.G1 phase
c.M phase
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26.Facial palsy in Herpes Zoster seen in
a.Ramsay hunt syndrome
b.Meckerson Rosenthal syndrome
Ans :
27.Crouzan syndrome is associated with
a.retinitis pigmentosa
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28.Trinucleotide repeat sequence defect is not seen in
a.huntingtons
b.alzhiemers
c.freidricks ataxia
Ans:
29.An elderly man with ataxic hemiparesis,diagnosis is
a.cerebellar hemorrhage
Ans:
30.A 60 yrs man with previous episodes of ataxia ,diplopia,dizziness, now presents with sudden headache and altered sensorium,diagnosis is
a.pontine hge
b.cerebellar he
Ans:

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11.Pyoderma gangrenosum is
a.common in diabetics
b.common in elderly
c. commonly due to pseudomonas aeruginosa
Ans:
12. An elderly man with sigmoid volvulus,successfully detorsed.what is the next step.
a. Reassurance
b. resection immediately
c. resection if volvulus recurs
Ans:
13.Number of copies of HIV DNA to start HAART
a.5000 copies/ml
b.20000 copies/ml
c.50000 copies/ml
Ans:
14.Indication of PCR in diagnosis of HIV
a.when western blot is indeterminate
b.when one elisa is positive and other elisa is negative
c. when both elisa positive but western blot negative
Ans :
15.Contraindication of laprascopic surgery except
a.third trimester pregnancy
b.emphysema
c.portal hypertension
d.Generalised Periotonitis.
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16.Example of secondary prevention
a.thrombolysis in acute MI
b.cholesterol lowering drug in CAD
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17. Gamma Glutamyl Transferase increased in
a.alcoholic hepatitis
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18.An alcoholic with ascites,bloody tap,elevated alfa fetoprotien,diagnosis is
a.choriocarcinoma
b.hepatocellular Ca
Ans:
19.Toxin for lathyrism
a.BOAA
b.sanguinarine
c.pyrazolidine alkaloid
Ans:

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31.Lewis body seen in
a.parkinsonism
Ans :
32.Nissin’s substance is seen in
a. cell body
b. axon
c. dendrites
Ans:
33.A 24 yr old lady with 24 hrs pain in right iliac fossa,vomiting,central dyspareunia,rebound tenderness present,temperature 37 degree.Pregnancy test negative .diagnosis is
a. acute appendicitis
b. acute PID
Ans:
34.A Patient is on ampicillin,has developed abdominal colic,distention,diarrohea. sigmoidoscopy reveals thick yellowish mucosa,what is the drug of choice.
a. vancomycin
Ans:
35.An elderly with sudden onset of headache and altered sensorium is diagnosed to have sub arachnoid hemorrhage.what is the best investigation of choice
a. CT Scan
Ans:
36.following is a feature of Medial Medullary syndrome
a. ipsilateral horner syndrome
b.ipsilateral loss of pain and temperature
c. ipsilateral loss of position and vibration sense.
Ans:
37.Most common site of berry aneurysm
a. anterior circulation
Ans:
38.true about catheter associated UTI
a. Most catheter asso UTI patients are symptomatic
b.significant bacteriuria occurs in patients catheterised longer than 2 weeks
c.most commonly infection is due to staph and strepto
Ans:
39.following injury to right temple region ,patient complained of pain in the rt.eye and
loss of vision . On examination eye movements are normal,pupil normally reacts to light
diagnosis is
a. functional loss of vision
b. optic nerve atrophy
Ans:
40.Following head injury , rushing sound heard inside the head,
a. carotid fistula
Ans:
41.An elderly man with painful red eye, pupil dilated and fixed,what is the next investigation
a.tonometry
b.visual evoked potential
Ans:
42.vibration sense is carried by
a. pacinian corpuscles
b.meckels
c.ruffinis
d.free nerve endings
Ans:
43.A stab injury at the level of T 8,the following is seen except
a.ipsilateral loss of pain and temperature
b.ipsilateral loss of position sense
Ans:
44.Rheumatoid arthritis commonly affects
a.cervical spine
b.thoracic
c.lumbar
d.lumbosacral
Ans:
45.Most common cause of embolism causing cerebro vascular disease is
a.prosthetic valves
b.non rheumatic atrial fibrillation
Ans :
46.Firm, warty vegetations along the line of closure of valve is seen in
a.sub acute bacterial endocarditis
b.rheumatic heart disease
c.Libmann sacks endocarditis
Ans:
47.Features of meningitis in newborn except
a.lethargy
b.neck stiffness
c.vomiting
Ans:
48. most common cause of perinatal mortality
a. birth trauma
b.birth asphyxia
c.congenital anomaly
Ans:
49.cause of Progressive Multi Focal Leuco encephalopathy is
a. HIV
b.J C virus
c. HTLV
Ans:

50.which is not a human disease.
a.scrapie
b.creutz felt jacob disease
Ans:
51.MC malignancy in childhood
a.ALL
b.bone tumor
Ans:
52.True about ewing’s sarcoma
a.responds well to radiotherapy
b.grows in diaphysis of long bones
Ans:
53. Tumor that develops from metaphysis
a.osteosarcoma
b.gaint cell tumor
Ans:
54.MC Benign tumor in less than 20 years age group
a.osteochondroma
Ans:
55.true about mammography
a.distinguishes benign from malignant tumor
b.can detect even non palpable masses.
Ans :
56.Most important feature characteristic of breast malignancy in young age
a. bloody discharge
b.puckered breast skin
Ans:
57.true about fibrocystic disease
a.usually unilateral
b.pre cancerous
c.cyclical mastalgia
Ans:
58.Role of tamoxifen in the reduction of breast cancer
a.competes with estrogen receptor in breast
Ans;
59.true about Follicular Ca of thyroid except
a. usually spread thro lymphnode
Ans:
60.Pheochromocytoma associated with
a.Von Hippel Lindau syndrome
Ans:
61.In Sturge weber syndrome, all are seen except

62.A Child is diagnosed to have tuberous sclerosis.which of the following skin lesion is associated.
a.ash leaf spot
b.shagreen patches
c.adenoma sebacium
Ans:
63.Acanthosis nigricans is most commonly associated with
a.Genitourinary malignancy
b.Gastrointestinal malignancy
Ans:
64.MC pancreatic tumor
a. Insulinoma
b.Beta cell tumor
Ans:
65.A 62 year man is prescribed a pharmaceutical agent that found to inhibit
HMG- CO A Reductase. What could be the diagnosis
a. Type 2 Diabetes
b.Familial Hypercholesterolemia
Ans:
66.The lipid lowering drug to be avoided in diabetics as it worsens the glycemic profile is
a. Niacin
b.Statins
c.Gemfibrozil
d.Clofibrate
Ans:
67.The following are Unconjugated Hyperbilirubinemia except
a.Criggler Najar Type 1
b.Gilberts
c. Dubin Johnson synd
d. Criggler Najar Type 2
Ans:
68.A female child of a mother is diagnosed to have Duchenne’s muscular dystrophy.
What risk does the mother have for her next male child to suffer from similar illness
a.25%
b.50%
c.100%
d.0%
Ans:
69.Purpose of Randomised controlled trial
a. to minimise the selection bias
Ans:
70.Bhopal gas tragedy is
a.point source epidemic
b.propagated epidemic
c.common source
Ans:
71.Association between TB and Smoking is due to
a.selection bias
b.surveillance bias
c.recall bias
d.interviewer bias
Ans:
72.A Test with high sensitivity and low specificity will have
a.high true positives
b.high false negtives
c.less true negatives
Ans:
73.Cholera outbreak in three villages.few died.study suitable to find the source is
a.case control study
b.concurrent cohort study
c.cross sectional study
d.experimental study
Ans:
74.Skin lesion characteristic of Lyme’s disease
a.Erythema gyratum repens
b.Erythema migrans
c.Erythema marginatum
Ans:
75.Bacteremia is characteristic of
a.enteric fever
b.shigellosis
c.cholera
d.diptheria
Ans:
76.Carnitine defeciency impairs
a. fatty oxidation
b. fatty acid synthesis
c.mobilization of stored triglyceride
Ans:
77.Deficiency of which mineral causes diabetes melleitus
a.Zinc
b.Chromium
c.Iron
Ans:
78.0.45% Nacl is used in the treatment of
a.SIADH
b.Neurogenic diabetes insipidus
c.salt wasting cerebral disease
d.Hypernatremia
Ans:
79.All are ectodermal derivatives except
a. neuron
b.microglia
Ans:

80.self antigen and non self antigen is distinguished by
a.T cell
b.B cell
c.Monocyte
d.Macrophage
Ans:
81.Blood brain barrier is formed by
a. astrocytes
b.endothelial cells
Ans:
82. brain receives
a. 20% of cardiac output
b. 10% of cardiac output
c. 5% of cardiac output
Ans:
83.BBB is not found in
a. pineal body
b. mamillary body
Ans:
84.Circadian rhythm is regulated by
a.Supra chiasmatic nucleus
Ans:
85. An elderly man with tremors,with family history of dementia ,diagnosis is
a. alzhiemers
b.parkinsonism dementia – ALS complex
Ans:
86. true about essential tremor

87.common type of hallucination in scheizophrenia
a.auditory
b.visual
c.olfactory
Ans:
88.Electro convulsive therapy indicated in which type
a.catatonic scheizophrenia
b.paranoid
Ans:
89.Agarophobia is fear of
a.Meeting strangers
b.Heights
c.places where escape is difficult
d.crowd
Ans:
90.A lady used to repeatedly wash her hands due to the fear of acquiring AIDS is due to
a.OCD
Ans:
91.Anterior spinal artery thrombosis results in

92.In L4-L5 Disc prolapse, nerve involved is
a.L4
b.L5.
Ans:
93.Meralgia paresthetica is due to
a.lateral cutaneous nerve of thigh
Ans:
94.A 5 yr boy with fracture in shaft of humerus,how to exclude radial nerve involvement
a.inability in flexion of forearm and loss of sensation in lateral forearm
b.inability in extension of wrist and loss of sensation in area over anatomical snuff
box.
Ans:
95.CSF findings : protein -60%, sugar – 40%,neutrophils predominant, diagnosis is
a.viral meningitis
b.bacterial meningitis
c.TB meningitis
Ans:
96.daily production of CSF
a.550 ml
b.1000 ml
Ans:
97.Regarding post spinal headache , true except
a. occurs within 48 hrs
b. increased by sitting
c. due to CSF Leak
d.
Ans:
[snip].All are side effects of Hydralazine except
a. Lupus synd
Ans:
99. Delta waves in ECG is characteristic of
a.Wolf Parkinson White syndrome
Ans:
100.find the incorrect match
a. fatty liver – tetracycline
b.hepatitis – halothane
c. granuloma – chlorpromazine
d. cholestasis – erythromycin
Ans:

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101.Complication of colles # except
a.shoulder hand syndrome
b.non union
c. rupture of EPL tendon
d.carpal tunnel syndrome
Ans:

102.Best to evaluate alpha interferon therapy for HCV
a. quantification of HCV RNA
Ans:
103.In muscle splitting procedure for appendicectomy, the following are encountered except
a.external aponeurosis
b.superficial membranus fascia
c.rectus abdominis
d.peritoneum
Ans:
104.A cystic , transilluminant painless scrotal swelling,testes separately palpable, the procedure done is
a.Lords’ procedure
b.Hunters’ procedure
Ans:
105.Gold standard investigation for GERD is
a.24 hr pH monitoring
Ans:
106. MC Type of Ca of urinary bladder
a.Squamous cell Ca
b.Transitional cell Ca
Ans :
107.All are structures in hepato duodenal ligament except
a.hepatic vein
b.portal vein
c.CBD
d.cystic duct
Ans:
108. Hexagonal stone is
a. cystine stone
b. uric acid stone
c.triple phosphate stone
d.calcium oxalate stone
Ans:
109.risk factor for pre eclampsia except
a.multiparity
b.DM
Ans:
110.Scale for sexual maturity
a. tanners’ scale
b. glasgow scale
Ans:
111. benzodizapine antagonist
a. Flumazenil
112.Paralysis of adductor pollicis,hypothenar muscle weakness ,loss of sensation in palmar and dorsal aspect of 4th and 5th finger.where is the site of lesion
a.wrist
b. ? canal
Ans:
113.find the incorrect match :
a.Raphe nucleus – serotonin
b.locus ceruleus – histamine
c.basal forebrain – Ach
d. substantia nigra – dopamine
Ans:
114.nucleus of meyernet is for
a. choline synthesis
Ans:
115.definitive host for tenia solium
a.pig
b.man
Ans:
116.water can heart shadow in x-ray is
a. pericardial effusion
Ans:
117. A young man had a stab injury in left 5th ICS at the mid clavicular line.there is no deviation of trachea ,heart sounds distantly heard,systolic BP 80mmHg,RR-20/min, diagnosis is
a. cardiac tamponade
b.massive left hemothorax
c. tension pneumothorax
Ans:
118.false about tension pneumo thorax
a.always air leaks from lungs to pleura
Ans:
119.In a case of lacunar infarct,what prophylaxis is preffered to prevent recurrent stroke attack.
a.asprin
b.asprin & clopidogrel
c.anticoagulant
d.shunt
Ans:
120.ECG feature of hyperkalemia
a.prolonged PR
b.Wide QRS
c. Prominent U Wave
d.Prolonged QT interval
Ans:
123.drug monitoring is required for
a.lithium
124.Programmed cell death is known as
a.apoptosis
125.all are typical antipsychotics except
a. risperidone
b. haloperidol
Ans:
126.true about Reyes’ syndrome except
a.follows viral infection
b.
Ans:
127.All are nucleoside reverse transcriptase inhibitors except
a.zidovudine
b.lamivudine
c.nevirapine
Ans:
128.In motor aphasia true except
a. impaired naming
b. impaired repetition
c.impaired fluency
d.preserved comprehension
Ans:
129.Cherry red spot seen in
a.CRVO
b. CRAO
Ans:
130.Leisch nodules seen in
a. SLE
Ans:
131.A pregnant lady of 10 wks, with her sister having a down syndrome baby wanted to terminate her pregnancy if her foetus is also downs.what investigation to do ?
a. amniocentesis
b. chorionic villous sampling
c. triple serum test
Ans:
132. the following transmitter is not a protein/glycopeptide/ polypeptide
a.serotonin
b.dynorphin
c.substance P
d.Met – enkephalin
Ans:
133.clostridium tetani effect is due to
a.endotoxin
b.exotoxin
c.antigen antibody complex
d.immune complex
Ans:
134. congenital hypogonadism in
a.kaplan syndrome
b.sheehans synd
Ans:
135.True about Syringomyelia
a. more than half the cases are associated with chiari malformation
b. symptoms typically begin in middle age
c. vibration & position sensation are usually diminished
d. Syrinx cavities are always congenital
Ans :
136.the antibody seen in drug induced SLE
a. anti histone antibody
Ans:
137.loop diuretics act at
a. PCT
b. DCT
c. Ascending loop
d. Descending loop
Ans:
138. A man with headache and confusion, what should be evaluated to clinch the diagnosis. ( I couldn’t reacall this question correctly)
a. photophobia and phonophobia
Ans:

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