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Dr_Saha · Credits: 6221 My Scrapbook

Dear friends,
so here I am starting the discussion from today .
we will start with neurology today .
below I am sharing some problems[in question formate] with you which are constructed to ignite the discussion procedure .
now as I have started this page of this forum I will make a open appeal to every serious member who visits this page. That is pls type all the related material you want to type in one place & then post it [ each time you post]; so every members message at the time of posting can be seen in limited space in one place. It probably becomes boring to read single lines at big big gaps [ take it easy its just a request , you are free to write as you want bcos ur participation is imp for us].
Some tips before you start answering
1. answer in chronology
2. use appropriate question no. to answer [it makes things easier to read & understand for other viewers]
3. pls don’t refer to book while you answer bcos no one is going to scold you if you answer wrong. [you may refer to book after you have finished answering ]. If you answer honestly you can judge ur knowledge & logic power. Above all you make mistake now probably you don’t make it again.
4. you are encouraged to attempt every question
5. try to justify [I mean explain with logic] every answer of urs on the basis of sound biomedical & clinical knowledge you have.

Here goes the first question set for discussion - SET-1

SET -1

1. foot process of what surrounds the capillaries at BBB[bl. Brain barier]?
2. what is the effect of endorphin as a neurotransmiter– excitatory or inhibitory?
3. which cell lines the cerebral ventricle?
4. name the anatomical structure essential for surrounding axon & transmit axn potential via saltatory conduction?
5. which cells form myelin sheath?
6. in pain to occur which neuropeptide plays the most imp role ?
7. during neuro transmission which specific event causes fusion of synaptic vesicles containing neurotransmitter to presynaptic membrane ?
8. mention any 2 very common causes of headache in elderly population ?
9. a 65 yr old pt came to ur clinic with history of severe headache . acording to him the pain precipitated while he was eating meat & bread in his sons 25th birthday. On neurologic exam you found the pain to be more in 5th nv area. What is most probable dx you will make before you proceede for any furthur investigation?
10. a lady who is married for last 8 yrs & has 1 male child comes to you with history of migraine with aura. She also gives history of using OCPs for last 5 years .
a. will you advice to continue her with same contraceptive device or you want to change it?
b. If you change it state why you want to change it? [ ur answer must be relevant to the above mentioned case]
11. a 32 yr old pt went to his physician with complain of aute onset severe headache just after sexual intercourse at early morning. His physician adviced him to undergo a CT scan . he had no similar previous history.
a. now do you think his physicians approach to his pt is correct?
b. If you support his approach justify why?
c. If you were the physician would you had ordered any additional investigation?
d. If yes what would you had ordered & why?

WELL FRIENDS I HOPE You LIKE THE APPROACH. PLS VOTE ME SO THAT I CAN EVALUATE MY SELF.
UR ADVICE/CRITICISM TO ENRICH THE DISCUSSION PROCEDURE IS AWAITED.
FOR EXHAUSTIVE DISCUSSION ON MANY OTHER TOPICS PM ME WITH UR E-MAIL ADDRESS [[snip] PREFFERED], BCOS DISCUSSION IN THIS PAGE WILL BE A QUITE SLOW PROCESS BCOS TILL WE HAVE ENOUGH DISCUSSION by enough no. of participants I CANT KEEP the SET-2 FOR DISCUSSION.
HOPE You LIKE IT.
HAPPY STUDYING
Dr. Saha

INTERN07 · Credits: 226 My Scrapbook

i wanna join it...

dr_ekta · Credits: 195 My Scrapbook

dr_ekta · Credits: 195 My Scrapbook

Hi Dr. saha. I wish to join next week for online discussion.. busy with my rural posting.... Till then continue ur job.. Have a studious time...Dr.Ekta

Dr_Saha · Credits: 6221 My Scrapbook

yes ekta unfortunately the discussion has started in a similar thread.
actually i wanted to bring everyone in this thread but the discusssion started there.

so i will post set -2 in this and that thread ; lets see what visitors off these threads say.

only thing is in this thread there is a poll which is not there[but its essential for evaluation]

any way.

be back soon
Dr saha

dr_ekta · Credits: 195 My Scrapbook

Dr_Saha · Credits: 6221 My Scrapbook

advice me Dr ekta how to introduce poll in the other thread.

Dr saha

Dr_Saha · Credits: 6221 My Scrapbook

Dear friends,
oh no; thanx a lot for the nice feedbacks of govindraj and dr ekta.
i was confused whether to continue it in the same thread or in a new thread.

well govind hematology set will be the next set i.e. set -3 and thats my promise.

being inspired by the positive feed back u gave me, here I am back with SET -2 for discussion.

Set 2 is about Biochemistry .
Try to answer as many as possible.

Here goes the questions-

SET -2

1 what is the distance spanned by 1 complete turn of DNA ?

2 during DNA replication when unwinding occurs which specific protein helps in maintaining the single stranded conformation so that replication can continue smoothly?

3 during DNA replication to which end of the DNA strand do a DNA polymerase adds a nucleotide?

4 in humans during DNA replication how many neucleotides are polymerised per second by the DNA polymerase?

5 how long does a entire mammalian genome take to replicate?

6 during which phase of cell cycle DNA polymerase contains in mammalian cells is highest in quantity?

7 which mechanism of DNA repair is diminished or damaged in xeoderma pigmentosum?

8 what is the direction of phosphodiester backbone in a DNA strand?

[ answers of set 1-

ans of question 1>astrocytes
Ans of question 2> both inhibitory and excitatory
Ans of question 3>ependymal tissue
Ans of question 4>myelin sheath
Ans of question 5>oligodendrocytes

Ans of question 6> substance P

Ans of question 7> entry of calcium ion

Ans for question 10> not only it will aggravate migraine there is another more important thing we are concerned of; that is wheneever a patient has migraine with aura & simultaneously history of use of ocps there is a INCREASED risk of having stroke in future.

Ans of question11 >
[a] yes correct
bcos history indicates it may be a sub – arachnoid hemorrhage ]

LET ME KNOW UR FEED BACK ABOUT HOW You Are FEELING WITH THESE SETS ; Are THEY WORTHFUL.

PM ME FOR EXHAUSTIVE DISCUSSION ON ANY TOPIC .

EVEN You DON’T KNOW ALL THE ANSWERS NO MATTER , REPLY AS MUCH You KNOW.

HOPE THIS THREAD IS HELPFUL.

once again thanx to govind and ekta for guiding how to continue the thread.

THANX FOR READING.

HAPPY LEARNING.

Dr Saha

Dr_Saha · Credits: 6221 My Scrapbook

hello visitors
answer of set-2
and topics of set 3
will be posted on 8th aug-2007.

set 3 will contain hematology.

thanx
Dr saha

Dr_Saha · Credits: 6221 My Scrapbook

Dear friends ,

actual discussion is going on a similar thread titled - STUDY PARTNERS-GROUP discussion- for AIIMS /AIPGE aready started JOIN US.

so that u don t miss the discussions the same set 3 is posted here.

Being inspired form so many visitors encouragement [some inspired me in the other thread and some had pm me] here goes the SET-3 , CONTAINT OF WHICH IS HEMATOLOGY.

At first we will visit the answers of set -2 then go for SET -3

ANSWERS OF SET-2
1) 3.4 nm
2) SSB PROTEIN
3) 3’ END
4) 100 NEUCLEOTIDES PER SECOND
5) APPROXIMATELY 9 HOURS
6) S – PHASE
7) NUCLEOTIDE EXCISION REPAIR PROCESS
8) 5’-3’

SET-3 - HEMATOLOGY

1) WHAT IS THE SHAPE OF RBC?

2) WHAT DO You THINK IS THE PHYSIOLOGICAL IMPORTANCE OF THIS TYPICAL SHAPE?

3) IN HEMOLYTIC Anemia ERYTHROPOIESIS IN BONE MARROW DECREASE - T/F [TRUE / FALSE]

4) MEAN CELL VOL IS EXPRESSED IN CUBIC MICROMETERS. – T/F

5) YOUR PATIENT RINKU HAS HEREDITARY SPHEROCYTOSIS. WHICH STRUCTURE OF RINKUS RED BLOOD CELL IS AFFECTED You THINK?

6) NAME THE GLOBIN CHAINS PRESENT IN FETAL Hb ?

7) ALPHA THALASEMIA IS CAUSED BY DEFICIENT SYNTHESIS OF GAMMA CHAIN. – T/F

8) SPLICING MUTATION CAN CAUSE BETA THALASEMIA- T/F

9) WRITE ANY 4 CAUSES OF NON-THROMBOCYTOPENIC PURPURA.

10) WHAT IS EHLERS – DANLOS SYNDROME?

11) Mrs J. HOPKINS HAS TO UNDER GO SPLEENECTOMY. SURGEON INSTRUCTED You TO VACCINATE THE PATIENT BEFORE SPLEENECTOMY. NOW AGAINST WHICH MICRO –ORGANISMS WILL You VACCINATE HER?

12) WHICH COAGULATION FACTOR IS DEFICIENT IN HEMOPHILIA –A ?

13) WHAT IS THE HALF LIFE OF HEPARIN?

14) UR PATIENT WHO IS ON HEPARIN IS BLEEDING SEVERELY. BESIDES MONITORING THE TRANSFUSION OF HEPARIN WHAT SPECIFIC AGENT WILL You USE TO NEUTRALISE THE HEPARIN?

15) WHAT IS THE MOST COMMON SIDE EFFECT OF WARFARIN?

LET ME KNOW UR FEED BACK ABOUT HOW YOU ARE FEELING WITH THESE SETS ; ARE THEY WORTHFUL.

PM ME FOR EXHAUSTIVE DISCUSSION ON ANY TOPIC .

EVEN YOU DON’T KNOW ALL THE ANSWERS NO MATTER , REPLY AS MUCH YOU KNOW.

HOPE THIS THREAD IS HELPFUL.

THANKING YOU.

Dr. Saha
08/AUG/2007

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