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sabdongSend an Instant Message to sabdong  




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Quick Scroll neurology : huntington's disease 08.16.07 (11 months ago) #1
A 45 YO male is brought to the ER by his family, who has noted him to be behaving bizarrely. There is a family history of early death. He is unable to control pronounced choreiform mvts o his upper extremities and trunk. Which of the foll is the most likely neurotransmitter disturbance?

A depletion of acetylcholine
B depletion of dopamine
C depletion of gamma-aminobutyric acid
D excessive production of acetylcholine
E excessive production of dopamine
F excessive production of gamma-aminobutyric acid
G excessive production of norepinephrine
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Quick Scroll 08.16.07 (11 months ago) #2
my diagnosis is Huntingtons disease if its correct then the answer might be C - GABA is less in HD so chorea icon_rolleyes.gif
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Quick Scroll 08.16.07 (11 months ago) #3
agreed
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Quick Scroll 08.17.07 (11 months ago) #4
Depletion of gamma-butyric acid. Huntington's chorea
Onset in 5 th decade AD
involve choreaform movements, cognitive disturbance
emotional dysfunction-
Atrophy of caudate nucleus - DEPLETION OF GABA

excessive amounts of DA----> SCHIZOPHRENIA
depletion of ACH------> alzheimer's
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